merck millipore,默克密理愽
  • merck millipore,默克密理博,07-613,Anti-Thioredoxin Reductase 1 (TrxR1) Antibody

  • merck millipore,默克密理博,07-613,Anti-Thioredoxin Reductase 1 (TrxR1) Antibody

    产品名称：Anti-Thioredoxin Reductase 1 (TrxR1) Antibody
    产品型号：07-613
    Anti-Thioredoxin Reductase 1 (TrxR1) Antibody is an antibody against Thioredoxin Reductase 1 (TrxR1) for use in WB & IC.

    merck millipore,默克密理博,07-613,Anti-Thioredoxin Reductase 1 (TrxR1) Antibody

  • 产品介绍
  • merck millipore,默克密理博,07-613,Anti-Thioredoxin Reductase 1 (TrxR1) Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, HICC, WBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 07-613
    品牌系列 Upstate
    商名
    • Upstate
    描述 Anti-Thioredoxin Reductase 1 (TrxR1) Antibody
    产品信息
    格式 Affinity Purified
    演示 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
    应用
    应用 Anti-Thioredoxin Reductase 1 (TrxR1) Antibody is an antibody against Thioredoxin Reductase 1 (TrxR1) for use in WB & IC.
    主要应用
    • Immunocytochemistry
    • Western Blotting
    生物信息
    免疫原品种 peptide corresponding to amino acids 137-150 (C-PHRIKATNNKGKEK) of human thioredoxin reductase 1
    宿主 Rabbit
    特异性 thioredoxin reductase 1
    同种型 IgG
    品种反应性 RatHuman
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_003330
    Entrez基因汇总 This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.
    基因符号
    • TR1
    • TXNRD1
    • TXNR
    • oxidoreductase
    • TRXR1
    • Trxr1
    • MGC9145
    • TR
    • GRIM-12
    纯化方法 Immunoaffinity purified
    UniProt编号
    • Q16881
    UniProt汇总 COFACTOR: Binds 1 FAD per subunit.
    SIZE: 499 amino acids; 54707 Da
    SUBUNIT: Homodimer.
    SUBCELLULAR LOCATION: Cytoplasm (By similarity).
    PTM: The N-terminus is blocked. & Contains a selenide-sulfide bond between Cys-497 and Sec-498. This bond is speculated to serve as redox active pair (By similarity).
    SIMILARITY: SwissProt: Q16881 ## Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
    MISCELLANEOUS: The active site is a redox-active disulfide bond.
    产品使用声明
    质量保证 routinely evaluated by immunoblot in RIPA lysates from rat brain microsomal preparation
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 1 year at -20°C
    包装信息
    数量 100 µg

    merck millipore,默克密理博,07-613,Anti-Thioredoxin Reductase 1 (TrxR1) Antibody

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