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merck millipore,默克密理博,09-090,Anti-CHD9 Antibody
产品名称：Anti-CHD9 Antibody
产品型号：09-090
Anti-CHD9 Antibody is a Rabbit Polyclonal Antibody for detection of CHD9 also known as ATP-dependent helicase CHD9 or Chromatin-related mesenchymal modulator & has been validated in WB, ICC.
merck millipore,默克密理博,09-090,Anti-CHD9 Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 Eq, H, R, M, Chp ICC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 09-090 描述 Anti-CHD9 Antibody Alternate Names - ciprofibrate bound protein p240
- ATP-dependent helicase CHD9
- Chromatin-related mesenchymal modulator
- Chromatin-remodeling factor CHROM1
- Kismet homolog 2
- PPAR-alpha-interacting complex protein 320 kDa
- PPAR{gamma}-interacting cofactor 320 kDa
- Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein
- chromatin remodeling factor CHROM1
- chromodomain helicase DNA binding protein 9
背景信息 CHD9 is a member of the chromodomain-helicase-DNA-binding family of proteins. Consistent with other members of this family this protein functions as an ATP-dependent chromatin remodeling protein that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. CHD9 has been shown to possess DNA-dependent ATPase activity and to associate with A/T-rich regulatory regions in promoters of genes that participate in the differentiation of progenitors during osteogenesis. The CHD9 protein is a member of the SNF2/RAD54 helicase family and contains two chromodomains (chromatin organization modifiers), single helicase/ATPase domain, as well as a helicase C-terminal domain.
This protein is found in both the cytoplasm and nucleus and can be phosphorylated on serine and tyrosine residues. This protein is widely expressed in a variety of tissues at at low levels. In bone marrow, expression is restricted to osteoprogenitor cells adjacent to mature osteoblasts.
CHD9 has been shown to interact with PPARA to function as a transcriptional coactivator. This protein also possibly interacts with other nuclear receptors such as with ESR1 (Estrogen Receptor-alpha) and NR1I3 (constitutive androstane receptor/CAR).产品信息 格式 Affinity Purified 控制 - HeLa cell lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide. 应用 应用 Anti-CHD9 Antibody is a Rabbit Polyclonal Antibody for detection of CHD9 also known as ATP-dependent helicase CHD9 or Chromatin-related mesenchymal modulator & has been validated in WB, ICC. 主要应用 - Immunocytochemistry
- Western Blotting
应用说明 Imunocytochemistry Analysis: 1:500 dilution from a previous lot detected CHD9 in HeLa and A431 cells. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human CHD9. 表位 Linear peptide correponding to internal region between amino acids 2580-2610 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes CHD9. 品种反应性 HorseHumanRatMouseChimpanzee Species Reactivity Note Demonstrated to react with human. Predicted to react with rat, mouse, chimpanzee, and equine based on 100% sequence homology. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_079410
基因符号 - proteinx0008
- CHD9
- AD013
- BC022889
- CHD-9
- CReMM
- KISH2
- PRIC320
纯化方法 Affinity Purfied UniProt编号 - Q3L8U1
UniProt汇总 FUNCTION: Acts as a transcriptional coactivator for PPARA and possibly other nuclear receptors. Proposed to be a ATP-dependent chromatin remodeling protein. Has DNA-dependent ATPase activity and binds to A/T-rich DNA. Associates with A/T-rich regulatory regions in promoters of genes that participate in the differentiation of progenitors during osteogenesis By similarity.
SUBUNIT STRUCTURE: Interacts with PPARA. Probably interacts with ESR1 and NR1I3.
SUBCELLULAR LOCATION: Cytoplasm. Nucleus.
TISSUE SPECIFICTY: Widely expressed at low levels. In bone marrow, expression is restricted to osteoprogenitor cells adjacent to mature osteoblasts.
PTM: Phosphorylated on serine and tyrosine residues.
SEQUENCE SIMILARITIES: Belongs to the SNF2/RAD54 helicase family.
Contains 2 chromo domains.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase C-terminal domain.
SEQUENCE CAUTION: The sequence AAF24170.1 differs from that shown. Reason: Erroneous translation. Wrong choice of frame.产品使用声明 质量保证 Evaluated by Western Blot in HeLa cell lysate.
Western Blot Analysis: 0.1 µg/ml of this antibody detected CHD9 on 10 µg of HeLa cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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