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merck millipore,默克密理博,434610,Leukadherin-1 - Calbiochem
产品名称：Leukadherin-1 - Calbiochem
产品型号：434610
A furanyl thiazolidinone compound that binds CD11b αA/αI domain in a reversible manner and stabilizes αA in a high-affinity binding conformation toward known CD11b/CD18 (αMβ2; CR3; Mac-1) ligands, fib More>>
merck millipore,默克密理博,434610,Leukadherin-1 - Calbiochem
- 产品介绍
重要规格表
经验配方 C₂₂H₁₅NO₄S₂ 描述 概述 A furanyl thiazolidinone compound that binds CD11b αA/αI domain in a reversible manner and stabilizes αA in a high-affinity binding conformation toward known CD11b/CD18 (αMβ2; CR3; Mac-1) ligands, fibrinogen, ICAM-1, and iC3B. Reported to be superior to IMB-10 (Cat. No. 407271) in enhancing Mac-1-mediated cell adhesion (EC50 = 4 vs. >50 µM on fibrinogen surface). Effectively suppresses leukocyte recruitment in various inflammatory disease models involving mice, rats, and zebrafish embryos in vivo. 产品目录编号 434610 品牌系列 Calbiochem®
同义词 LA1, Mac-1 Agonist II, CR3 Agonist II, CD11b/CD18 Agonist, 4-(5-((3-Benzyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)methyl)furan-2-yl)-benzoic acid, αMβ2 Agonist II, CD11b Agonist II 参考 参考 Maiguel, D., et al. 2011. Sci. Signal. 4, ra57. 产品信息 形式 Red-brown solid Hill配方 C₂₂H₁₅NO₄S₂ 化学配方 C₂₂H₁₅NO₄S₂ Molar Mass 421.5 结构配方图像 生物信息 纯度 ≥95% by HPLC 理化信息 溶解度 DMSO 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 +2°C to +8°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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