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  • merck millipore,默克密理博,07-561,Anti-phospho-eNOS/NOS III (Ser617) Antibody

  • merck millipore,默克密理博,07-561,Anti-phospho-eNOS/NOS III (Ser617) Antibody

    产品名称：Anti-phospho-eNOS/NOS III (Ser617) Antibody
    产品型号：07-561
    Anti-phospho-eNOS/NOS III (Ser617) Antibody detects level of phospho-eNOS/NOS III (Ser617) & has been published & validated for use in WB.

    merck millipore,默克密理博,07-561,Anti-phospho-eNOS/NOS III (Ser617) Antibody

  • 产品介绍
  • merck millipore,默克密理博,07-561,Anti-phospho-eNOS/NOS III (Ser617) Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    BWBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 07-561
    品牌系列 Upstate
    商名
    • Upstate
    描述 Anti-phospho-eNOS/NOS III (Ser617) Antibody
    概述 Note: ADMA (Catalog #19-169) and NMMA (Catalog #19-170) are inhibitors of NOS
    产品信息
    格式 Affinity Purified
    演示 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
    应用
    应用 Anti-phospho-eNOS/NOS III (Ser617) Antibody detects level of phospho-eNOS/NOS III (Ser617) & has been published & validated for use in WB.
    主要应用
    • Western Blotting
    生物信息
    免疫原品种 Peptide corresponding to amino acids surrounding phosphorylated Ser617 of eNOS/NOS III. This site corresponds to human Ser615.
    宿主 Rabbit
    特异性 phosphorylated eNOS/NOS III (Ser617)
    同种型 IgG
    品种反应性 Bovine
    Species Reactivity Note The immunizing sequence has 11/12 identical amino acids in mouse, and canine.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_000603
    基因符号
    • NOSIII
    • NOS3
    • cNOS
    • ECNOS
    • eNOS
    • EC-NOS
    修改
    • Phosphorylation
    纯化方法 Immunoaffinity purified
    UniProt编号
    • P29474
    UniProt汇总 FUNCTION: SwissProt: P29474 # Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. No mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.
    COFACTOR: Heme group. & Binds 1 FAD. & Binds 1 FMN. & Metrahydrobiopterin (BH4). May stabilize the dimeric form of the enzyme.
    SIZE: 1203 amino acids; 133289 Da
    SUBUNIT: Homodimer. Interacts with NOSIP and NOSTRIN.
    SUBCELLULAR LOCATION: Cell membrane, caveola. Cytoplasm, cytoskeleton. Golgi apparatus. Note=Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle; which is favored by interaction with NOSIP and results in a reduced enzymatic activity.
    TISSUE SPECIFICITY: Platelets, placenta, liver and kidney.
    SIMILARITY: SwissProt: P29474 ## Belongs to the NOS family. & Contains 1 flavodoxin-like domain.
    产品使用声明
    质量保证 routinely evaluated by immunoblot in RIPA lysates from fetal bovine heart endothelial (FBHE) cells
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 1 year at -20°C
    包装信息
    数量 200 µL

    merck millipore,默克密理博,07-561,Anti-phospho-eNOS/NOS III (Ser617) Antibody

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