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品种反应性 主要应用 宿主 格式 抗体类型 R, H WB Rb Serum Polyclonal Antibody 描述 产品目录编号 07-410 品牌系列 Upstate
商名 - Upstate
描述 Anti-WAVE2/Scar2 Antibody 产品信息 格式 Serum 演示 0.05% sodium azide before the addition of glycerol to 30% 应用 应用 This Anti-WAVE2/Scar2 Antibody is validated for use in WB for the detection of WAVE2/Scar2. 主要应用 - Western Blotting
生物信息 免疫原品种 peptide corresponding to amino acids 186-200 of human WAVE2/Scar2, with an N-terminal cysteine 宿主 Rabbit 特异性 WAVE2/Scar2 同种型 IgG 品种反应性 RatHuman 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_006990
Entrez基因汇总 This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X. 基因符号 - dJ393P12.2
- WASF2
- WAVE2
- IMD2
- SCAR2
纯化方法 Antiserum UniProt编号 - Q9Y6W5
UniProt汇总 FUNCTION: SwissProt: Q9Y6W5 # Downstream effector molecules involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton.
SIZE: 498 amino acids; 54284 Da
SUBUNIT: Binds actin and the Arp2/3 complex. Interacts with BAIAP2. Component of the WAVE2 complex composed of ABI1, CYFIP1/SRA1, NCKAP1/NAP1 and WASF2/WAVE2. Directly interacts with C3orf10/HSPC300.
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton (By similarity). Cell projection, lamellipodium (By similarity). Note=At the interface between the lamellipodial actin meshwork and the membrane (By similarity).
TISSUE SPECIFICITY: Expressed in all tissues with strongest expression in placenta, lung, and peripheral blood leukocytes, but not in skeletal muscle.
DOMAIN:SwissProt: Q9Y6W5 Binds the Arp2/3 complex through the C-terminal region and actin through verprolin homology (VPH) domain.
SIMILARITY: Contains 1 WH2 domain.产品使用声明 质量保证 routinely evaluated by immunoblot in in RIPA lysates from HL60 cells 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 200 µL
上一件merck millipore产品：merck millipore,默克密理博,09-817,Anti-JMJD1C Antibody
下一件merck millipore产品：merck millipore,默克密理博,MABN501,Anti-SUR1 Antibody, clone N289/16
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