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品种反应性 主要应用 宿主 格式 抗体类型 R, H, M WB Rb Purified Polyclonal Antibody 描述 产品目录编号 07-402 Replaces 04-391 品牌系列 Upstate
商名 - Upstate
描述 Anti-p70 S6 Kinase Antibody 产品信息 格式 Purified 演示 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30% 应用 应用 Anti-p70 S6 Kinase Antibody is an antibody against p70 S6 Kinase for use in IP & WB. 主要应用 - Western Blotting
生物信息 免疫原品种 peptide corresponding to amino acids 26-43 of rat p70 S6 Kinase, with an N-terminal cysteine 宿主 Rabbit 特异性 p70 S6 kinase 同种型 IgG 品种反应性 RatHumanMouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_003161
Entrez基因汇总 This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized. 基因符号 - PS6K
- RPS6KB1
- p70-alpha
- p70S6k
- p70-S6K
- p70
- S6K
- S6Kalpha)
- P70S6K
- STK14A
- S6K1
- p70(S6K)-alpha
纯化方法 Protein A purfied UniProt编号 - P23443
UniProt汇总 FUNCTION: SwissProt: P23443 # Phosphorylates specifically ribosomal protein S6 in response to insulin or several classes of mitogens.
SIZE: 525 amino acids; 59140 Da
SUBUNIT: Interacts with PPP1R9A/neurabin-1 (By similarity).
SUBCELLULAR LOCATION: Cytoplasm (By similarity). Cell junction, synapse, synaptosome (By similarity).
TISSUE SPECIFICITY: Widely expressed.
SIMILARITY: SwissProt: P23443 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 1 protein kinase domain.产品使用声明 质量保证 routinely evaluated by immunoblot in RIPA lysates from HEK293, PC-12,and A431 cells 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 200 µg
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