merck millipore,默克密理愽
  • merck millipore,默克密理博,573098,JAK2 Inhibitor III, SD-1029

  • merck millipore,默克密理博,573098,JAK2 Inhibitor III, SD-1029

    产品名称：JAK2 Inhibitor III, SD-1029
    产品型号：573098
    The JAK2 Inhibitor III, SD-1029, also referenced under CAS 118372-34-2, controls the biological activity of JAK2.

    merck millipore,默克密理博,573098,JAK2 Inhibitor III, SD-1029

  • 产品介绍
  • merck millipore,默克密理博,573098,JAK2 Inhibitor III, SD-1029

    重要规格表

    经验配方 CAS号
    C₂₅H₃₀Cl₂N₂O₃ • 2HBr118372-34-2
    描述
    概述 A cell-permeable xanthenedione compound that acts as a JAK2-selective inhibitor. It exhibits much less effect on the cellular phosphorylation levels of Jak1 and Src and shows no significant inhibition towards a panel of 49 other protein kinases in cell-free kinase assays at a concentration of 10 µM. Effectively inhibits cell proliferation in JAK-activated BA/F3 cell lines as well as phosphorylation and nuclear translocation of cellular Stat3.
    产品目录编号 573098
    品牌系列 Calbiochem®
    同义词 9-(3,4-Dichlorophenyl)-2,7-bis(dimethylaminomethyl)-3,4,5,6,7,9-hexahydro-2H-xanthene-1,8-dione, 2HBr, NSC 371488
    参考
    参考 Duan, Z., et al. 2006. Clin. Cancer Res. 12, 6844.
    产品信息
    CAS号 118372-34-2
    形式 Off-white solid
    Hill配方 C₂₅H₃₀Cl₂N₂O₃ • 2HBr
    化学配方 C₂₅H₃₀Cl₂N₂O₃ • 2HBr
    Molar Mass 639.3
    吸湿 Hygroscopic
    结构配方图像
    生物信息
    纯度 ≥80% by HPLC (sum of isomers)
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,573098,JAK2 Inhibitor III, SD-1029

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