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品种反应性 主要应用 宿主 格式 抗体类型 R, H, M ICC, WB Rb Purified Polyclonal Antibody 描述 产品目录编号 07-234 品牌系列 Upstate
商名 - Upstate
描述 Anti-REA Antibody 产品信息 格式 Purified 控制 - 3T3 nuclear extract
演示 200 μg of protein A purified rabbit IgG in 200 μL of 0.07 M Tris-glycine, pH 7.4, 0.105M NaCl, 0.035% sodium azide and 30% glycerol. 应用 应用 Detect REA with Anti-REA Antibody (Rabbit Polyclonal Antibody), that has been shown to work in IP, WB, ICC. 主要应用 - Immunocytochemistry
- Western Blotting
生物信息 免疫原品种 His6-tagged fusion protein corresponding to amino acid residues 88-299 of mouse REA-1/BAP-37/prohibitin-related protein 宿主 Rabbit 特异性 REA 同种型 IgG 品种反应性 RatHumanMouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_007273
基因符号 - Bap37
- PHB2
- BCAP37
- BAP
- Prohibitin-2
- REA
- D-prohibitin
- PNAS-141
- MGC117268
- p22
纯化方法 Protein A chromatography UniProt编号 - Q99623
UniProt汇总 FUNCTION: SwissProt: Q99623 # Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
SIZE: 299 amino acids; 33296 Da
SUBUNIT: Interacts with PHB, ESR1, HDAC1 and HDAC5 (By similarity).
SUBCELLULAR LOCATION: Mitochondrion inner membrane (By similarity). Cytoplasm (By similarity). Nucleus (By similarity). Note=Also cytoplasmic and nuclear (By similarity).
DEVELOPMENTAL STAGE: Levels of expression in fibroblasts decrease heterogeneously during cellular aging.
SIMILARITY: SwissProt: Q99623 ## Belongs to the prohibitin family.产品使用声明 质量保证 routinely evaluated by immunoblot on 3T3 nuclear extract 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 200 µg
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