merck millipore,默克密理愽
  • merck millipore,默克密理博,07-1224,Anti-PP6C Antibody

  • merck millipore,默克密理博,07-1224,Anti-PP6C Antibody

    产品名称：Anti-PP6C Antibody
    产品型号：07-1224
    Detect PP6C using this Anti-PP6C Antibody validated for use in WB, IP, IH(P).

    merck millipore,默克密理博,07-1224,Anti-PP6C Antibody

  • 产品介绍
  • merck millipore,默克密理博,07-1224,Anti-PP6C Antibody

    Replacement Information
    Replacement Information 07-1224 is a recommended replacement for AB4091

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, B, H, MWBRbPurifiedPolyclonal Antibody
    描述
    产品目录编号 07-1224
    Replaces AB4091
    描述 Anti-PP6C Antibody
    Alternate Names
    • Serine/threonine protein phosphatase catalytic subunit
    • H.sapiens mRNA for protein phosphatase 6
    • Serine/threonine-protein phosphatase 6
    • Protein phosphatase 6, catalytic subunit
    • catalytic subunit
    背景信息 This gene encodes the catalytic subunit of protein phosphatase, a component of a signaling pathway regulating cell cycle progression.
    产品信息
    格式 Purified
    控制
    • Jurkat Cell Lysate
    演示 Purified rabbit polyclonal IgG in buffer containing PBS with 0.08% sodium azide.
    应用
    应用 Detect PP6C using this Anti-PP6C Antibody validated for use in WB, IP, IH(P).
    主要应用
    • Western Blotting
    应用说明 Immunoprecipitation: A previous lot of this antibody was used in immunoprecipitation at a dilution of 10-20 µg/mL.
    Immunohistochemistry(paraffin):
    Optimal Staining of PP6 Polyclonal Antibody:
    Human Testis
    PP6 staining of round spermatids in normal human
    testis, tissue pretreated with citrate buffer, pH 6.0.
    Antibody was diluted 1:100, using IHC-Select®
    detection with HRP-DAB.
    生物信息
    免疫原品种 The immunogen used to the purified peptide conjugated to KLH corresponding to the sequence NH2-Cys-Ala-Val-Pro-Asp-Ser-Glu-Arg-Val-Ile- Pro-Pro-Arg-Thr-Thr-Thr-Pro-Tyr-COOH.
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Recognizes the catalytic subunit of Protein Phosphatase 6, MW ~33kDa.
    同种型 IgG
    品种反应性 RatBovineHumanMouse
    Species Reactivity Note Bovine; Human; Mouse; Rat
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_002721.3
    Entrez基因汇总 This gene encodes the catalytic subunit of protein phosphatase, a component of a signaling pathway regulating cell cycle progression. The N-terminal domain of this protein restricts G1 to S phase progression in cancer cells. Splice variants encoding different protein isoforms exist. The pseudogene of this gene is located on chromosome X.
    基因符号
    • EC 3.1.3.16
    • PPP6C
    • PP6
    • PPP6
    UniProt编号
    • O00743
    UniProt汇总 FUNCTION: SwissProt: O00743 # May function in cell cycle regulation.
    COFACTOR: Binds 1 iron ion per subunit (By similarity). & Binds 1 manganese ion per subunit (By similarity).
    SIZE: 305 amino acids; 35144 Da
    SUBCELLULAR LOCATION: Cytoplasm (By similarity).
    TISSUE SPECIFICITY: Highest expression levels in testis, heart, and skeletal muscle and lowest in placenta, lung and kidney.
    SIMILARITY: SwissProt: O00743 ## Belongs to the PPP phosphatase family. PP-6 (PP-V) subfamily.
    产品使用声明
    质量保证 Routinely evaluated by Western Blot on Jurkat lysates.

    Western Blot Analysis: 1:500 dilution of this lot detected PP6C on 10 μg of Jurkat lysates.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted aliquots for up to 1 year from date of receipt.
    Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,07-1224,Anti-PP6C Antibody

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