merck millipore,默克密理愽
  • merck millipore,默克密理博,07-1223,Anti-Protein Phosphatase 2 C α/β Antibody

  • merck millipore,默克密理博,07-1223,Anti-Protein Phosphatase 2 C α/β Antibody

    产品名称：Anti-Protein Phosphatase 2 C α/β Antibody
    产品型号：07-1223
    Detect Protein Phosphatase 2 C α/β using this Anti-Protein Phosphatase 2 C α/β Antibody validated for use in WB.

    merck millipore,默克密理博,07-1223,Anti-Protein Phosphatase 2 C α/β Antibody

  • 产品介绍
  • merck millipore,默克密理博,07-1223,Anti-Protein Phosphatase 2 C α/β Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, B, H, MWBRbPurifiedPolyclonal Antibody
    描述
    产品目录编号 07-1223
    Replaces AB4090
    描述 Anti-Protein Phosphatase 2 C α/β Antibody
    Alternate Names
    • Pyruvate dehydrogenase phosphatase
    • Protein phosphatase 2C
    • Pyruvate dehydrogenase
    • Pyruvate dehydrogenase phosphatase, catalytic subunit 1
    • Lipoamide-phosphatase 1, mitochondrial precursor
    • Protein phosphatase 2C, magnesium-dependent, catalytic subunit
    • Pyruvate dehydrogenase (Lipoamide) phosphatase-phosphatase
    • magnesium-dependent
    • catalytic subunit
    背景信息 PP-2 C α/β is heterodimer located in the mitochondrial matrix. Within the pyruvate dehydrogenase complex, PP-2 C α/β serves to catalyze the dephosphorylation and concomitant reactivation of the E1 component’s alpha subunit. Mutations occurring in the PDP1 gene are the cause of a disease known as pyruvate dehydrogenase deficiency (PDP deficiency), which leads to neurological dysfunction from lactic acidosis.
    产品信息
    格式 Purified
    控制
    • L6 Cell Lysate
    演示 Purified immunoglobulin in phosphate buffered saline with 0.08% sodium azide.
    应用
    应用 Detect Protein Phosphatase 2 C α/β using this Anti-Protein Phosphatase 2 C α/β Antibody validated for use in WB.
    主要应用
    • Western Blotting
    生物信息
    免疫原品种 Purified peptide conjugated to KLH.
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Recognizes the alpha/beta regulatory subunit isotype of protein phosphatase 2C (PP2C). PP 2C alpha/beta polyclonal antibody binds a 44-46 kDa protein.
    品种反应性 RatBovineHumanMouse
    Species Reactivity Note Proven to react with human and rat. Expected to react with mouse based on sequence homology.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • Q9P0J1
    基因符号
    • EC 3.1.3.43
    • PPM2C
    • PDPC
    • PDP1
    • FLJ32517
    • PDH
    • PDP
    • MGC119646
    纯化方法 Protein Purified
    UniProt编号
    • Q9P0J1
    UniProt汇总 FUNCTION: SwissProt: Q9P0J1 # Catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex (By similarity).
    COFACTOR: Binds 2 magnesium ions per subunit (By similarity).
    SIZE: 537 amino acids; 61054 Da
    SUBUNIT: Heterodimer of a catalytic subunit and a FAD protein of unknown function (By similarity).
    SUBCELLULAR LOCATION: Mitochondrion matrix (By similarity).
    DISEASE:SwissProt: Q9P0J1 # Defects in PDP1 are the cause of pyruvate dehydrogenase phosphatase deficiency (PDP deficiency) [MIM:608782]. PDP deficiency results in lactic acidosis leading to neurological dysfunction.
    SIMILARITY: SwissProt: Q9P0J1 ## Belongs to the PP2C family.
    产品使用声明
    质量保证 Evaluated by Western Blot in L6 cell lysates.
    Western Blot Analysis: 1:500 dilution of this lot detected PP-2 C ALPHA/BETA on 10 ug of L6 lysates.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted aliquots for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,07-1223,Anti-Protein Phosphatase 2 C α/β Antibody

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