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品种反应性 主要应用 宿主 格式 抗体类型 R, M WB, IHC Rb Purified Polyclonal Antibody 描述 产品目录编号 06-480 品牌系列 Upstate
商名 - Upstate
描述 Anti-Cathepsin B Antibody 产品信息 格式 Purified 控制 - A431 Cell Lysate
演示 Protein A Purified immunoglobulin. 0.1 M Tris-Glycine, 0.15 M NaCl, 0.05% sodium azide, pH 7.4. 应用 应用 Anti-Cathepsin B Antibody detects level of Cathepsin B & has been published & validated for use in IH & WB. 主要应用 - Western Blotting
- Immunohistochemistry
生物信息 免疫原品种 Recombinant rat procathepsin B 1 宿主 Rabbit 特异性 Recognizes procathepsin B and mature cathepsin B. 同种型 IgG 品种反应性 RatMouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_001908
Entrez基因汇总 The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. 基因符号 - APPS
- CTSB
- CPSB
纯化方法 Protein A purfied UniProt编号 - P07858
UniProt汇总 FUNCTION: SwissProt: P07858 # Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
SIZE: 339 amino acids; 37822 Da
SUBUNIT: Dimer of a heavy chain and a light chain cross-linked by a disulfide bond.
SUBCELLULAR LOCATION: Lysosome. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
SIMILARITY: SwissProt: P07858 ## Belongs to the peptidase C1 family.产品使用声明 质量保证 routinely evaluated by immunoblot on rat kidney microsomal preparation (Catalog #12-146) 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 包装信息 数量 400 µg 包装 2 vials of 200 μg
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