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merck millipore,默克密理博,06-457,Anti-Fms/CSF-1 R Antibody, extracellular domain
产品名称：Anti-Fms/CSF-1 R Antibody, extracellular domain
产品型号：06-457
Anti-Fms/CSF-1 R Antibody, extracellular domain detects level of Fms/CSF-1 R & has been published & validated for use in IP & WB.
merck millipore,默克密理博,06-457,Anti-Fms/CSF-1 R Antibody, extracellular domain
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Purified Polyclonal Antibody 描述 产品目录编号 06-457 品牌系列 Upstate
商名 - Upstate
描述 Anti-Fms/CSF-1 R Antibody, extracellular domain Alternate Names - CSF-1R
产品信息 格式 Purified 演示 0.1M Tris-glycine pH 7.4, 0.15M NaCl with 0.05% sodium azide 应用 应用 Anti-Fms/CSF-1 R Antibody, extracellular domain detects level of Fms/CSF-1 R & has been published & validated for use in IP & WB. 主要应用 - Western Blotting
生物信息 免疫原品种 RAB9 cells expressing the first 548 amino acids of human Fms encoded in a pLXSH retroviral vector 宿主 Rabbit 特异性 extracellular domain of human c-fms gene product (CSF-1 or M-CSF receptor) 同种型 IgG 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_005211
Entrez基因汇总 The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. 基因符号 - CSF-1R
- CSF1R
- C-FMS
- CSFR
- FIM2
- CSF-1-R
- c-fms
- CD115
- FMS
纯化方法 Protein G chromatography UniProt编号 - P07333
UniProt汇总 FUNCTION: SwissProt: P07333 # This protein is the receptor for CSF-1, it is a protein tyrosine-kinase transmembrane receptor.
SIZE: 972 amino acids; 107984 Da
SUBUNIT: Interacts with INPPL1/SHIP2 and THOC5 (By similarity).
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
TISSUE SPECIFICITY: Expressed in bone marrow and in differentiated blood mononuclear cells.
SIMILARITY: SwissProt: P07333 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. & Contains 5 Ig-like C2-type (immunoglobulin-like) domains. & Contains 1 protein kinase domain.产品使用声明 质量保证 routinely evaluated by immunoblot on 3T3/Fms cell lysates 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 200 µg
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