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merck millipore,默克密理博,06-243,Anti-TFIIB (NT) Antibody
产品名称：Anti-TFIIB (NT) Antibody
产品型号：06-243
Anti-TFIIB (N-Term) Antibody is a rabbit polyclonal antibody for detection of TFIIB (N-Term) also known as Transcription initiation factor IIB, RNA polymerase II transcription factor IIB & has been va More>>
merck millipore,默克密理博,06-243,Anti-TFIIB (NT) Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H, M WB Rb Purified Polyclonal Antibody 描述 产品目录编号 06-243 商名 - Upstate
描述 Anti-TFIIB (NT) Antibody Alternate Names - RNA polymerase II transcription factor IIB
- Transcription initiation factor IIB
- General transcription factor IIB
背景信息 TFIIB (GTF2B, TF2B, general transcription factor IIB) is a ubiquitously expressed transcription factor. TFIIB is essential for the formation of the RNA Polymerase II initiation complex. It is localized to the nucleus where it forms a complex with both TFIIA and TFIID (DAB complex). There it serves a linker between TFIID and RNA Polymerase II. TFIIB is also known to interact with POU3F2. 产品信息 格式 Purified 控制 - HeLa nuclear extract
演示 Affinity purified rabbit serum in 0.1M Tris-Glycine (pH7.4) 15mM NaCl, and 0.05% NaN3. 应用 应用 Anti-TFIIB (N-Term) Antibody is a rabbit polyclonal antibody for detection of TFIIB (N-Term) also known as Transcription initiation factor IIB, RNA polymerase II transcription factor IIB & has been validated in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 GST-tagged recombinant protein including amino acids 2-159 of TFIIB 表位 N-Term 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Detects TFIIB. 品种反应性 RatHumanMouse Species Reactivity Note Human. Mouse and Rat are expected to react as they share 99% homology. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_001505
Entrez基因汇总 This gene encodes the general transcription factor IIB,one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II. 基因符号 - TFIIB
- GTF2B
- TF2B
纯化方法 Antigen affinity purified UniProt编号 - Q00403
UniProt汇总 FUNCTION: General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II.Cofactor Binds 1 zinc ion per subunit.
SUBUNITS: Associates with TFIID-IIA (DA complex) to form TFIID-IIA-IIB (DAB-complex) which is then recognized by polymerase II. Interacts with the transcription elongation factor TCEA2. Interacts with HIV-1 Vpr. Interacts with GPBP1 By similarity.
SUBCELLULAR LOCATION: Nucleus.
SEQUENCE SIMILARITIES: Belongs to the TFIIB family.
Contains 1 TFIIB-type zinc finger.产品使用声明 质量保证 Routinely evaluated by Western Blot
Western Blot Analysis:
This lot detected TFIIB at 1:500 dilution in HeLa nulear extract lysates via SDS-PAGE and transferred to PVDF (Immobilon-P).使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt.
Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution.包装信息 数量 200 µL
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