merck millipore,默克密理愽
  • merck millipore,默克密理博,06-1091,Anti-IL-13 receptor Antibody, alpha-2 (IL-13RA2)

  • merck millipore,默克密理博,06-1091,Anti-IL-13 receptor Antibody, alpha-2 (IL-13RA2)

    产品名称：Anti-IL-13 receptor Antibody, alpha-2 (IL-13RA2)
    产品型号：06-1091
    Anti-IL-13 receptor Antibody, alpha-2 (IL-13RA2) is an antibody against IL-13 receptor for use in WB, IH(P).

    merck millipore,默克密理博,06-1091,Anti-IL-13 receptor Antibody, alpha-2 (IL-13RA2)

  • 产品介绍
  • merck millipore,默克密理博,06-1091,Anti-IL-13 receptor Antibody, alpha-2 (IL-13RA2)

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HWBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 06-1091
    描述 Anti-IL-13 receptor Antibody, alpha-2 (IL-13RA2)
    Alternate Names
    • CD213a2 antigen
    • interleukin 13 receptor, alpha 2
    • interleukin-13 receptor subunit alpha-2
    • interleukin 13 receptor alpha 2 chain
    • Interleukin-13-binding protein
    • IL-13R subunit alpha-2
    • cancer/testis antigen 19
    • IL-13 receptor subunit alpha-2
    • interleukin 13 binding protein
    • IL-13R-alpha-2
    背景信息 Interleukin-13 receptor subunit alpha-2 (IL-13RA2) is one receptor of Interleukin-13 which is a key moderator of asthma and allergic inflammation. IL-13 and its receptors have been shown to play a part in alcohol-mediated activation of pro-fibrotic pathways. IL-13 has a suppressive effect on macrophage activation but cannot activate T cells.
    产品信息
    格式 Affinity Purified
    控制
    • HeLa cell lysate
    演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Anti-IL-13 receptor Antibody, alpha-2 (IL-13RA2) is an antibody against IL-13 receptor for use in WB, IH(P).
    主要应用
    • Western Blotting
    应用说明 Western Blot (SNAP i.d.® Protein Detection System) Analysis: 5 µg/mL from a previous lot detected Interleukin-13 receptor, alpha-2 in 10 µg of HeLa cell lysate.

    Immunohistochemistry (paraffin) Analysis: A 1:500 dilution from a previous lot was used to detect Interleukin-13 receptor, alpha-2 in colorectal carcinoma and normal human kidney/medulla tissue sections.
    生物信息
    免疫原品种 KLH-conjugated linear peptide corresponding to human Interleukin-13 receptor, alpha-2 at the cytoplasmic domain.
    表位 Cytoplasmic Domain
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 This antibody recognizes Interleukin-13 receptor, alpha-2 at the cytoplasmic domain.
    品种反应性 Human
    Species Reactivity Note Demonstrated to react with human.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NP_000631
    Entrez基因汇总 The protein encoded by this gene is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13. [provided by RefSeq].
    基因符号
    • IL13R
    • IL13RA2
    • CD213a2
    • IL-13R
    • CT19
    • IL13BP
    • CD213A2
    • IL-13RA2
    纯化方法 Affinity Purified
    UniProt编号
    • Q14627
    UniProt汇总 FUNCTION: Binds as a monomer with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4).

    SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.

    DOMAIN: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.

    The box 1 motif is required for JAK interaction and/or activation.

    SEQUENCE SIMILARITIES: Belongs to the type I cytokine receptor family. Type 5 subfamily.

    Contains 1 fibronectin type-III domain.
    产品使用声明
    质量保证 Evaluated by Western Blot in HeLa cell lysate.

    Western Blot Analysis: 1 µg/mL of this antibody detected Interleukin-13 receptor, alpha-2 in 10 µg of HeLa cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,06-1091,Anti-IL-13 receptor Antibody, alpha-2 (IL-13RA2)

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