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品种反应性 主要应用 宿主 格式 抗体类型 Mk, H FC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 06-1081 描述 Anti-IL-26 Antibody Alternate Names - interleukin 26
- AK155 protein
背景信息 Interleukin 26 (IL-26) is a homodimer cytokine belonging to the IL-10 family that is expressed in certain herpesvirus-transformed T cells but not in primary stimulated T cells. Two such T cells are Th1 and Th17. IL-26 signals through a receptor complex comprising two distinct proteins called IL-20 receptor 1 and IL-10 receptor 2. By signaling through this receptor complex, IL-26 induces rapid phosphorylation of the transcription factors STAT1 and STAT3, which enhance IL-10 and IL-8 secretion and as expression of the CD54 molecule on the surface of epithelial cells. IL-26's function in human disease is unknown, however research has found that IL-26 expression is up-regulated in active Crohn's disease, and therefore may play an active role along with Th17 cells in various autoimmune diseases. 产品信息 格式 Affinity Purified 控制 - Recombinant human Interleukin 26 (IL-26).
演示 Purified rabbit polyclonal in PBS with 0.09% sodium azide. 应用 应用 Detect IL-26 using this Anti-IL-26 Antibody validated for use in WB, FC. 主要应用 - Flow Cytometry
- Western Blotting
应用说明 Flow Cytometry Analysis: 5 µg from a previous lot detected IL-26 in lymphocytes from human PBMC's.
Western Blot (SNAP ID) Analysis: 1 µg/mL from a previous lot detected recombinant human IL-26.生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human IL-26 near the C-terminus. 表位 Near the C-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes IL-26 near the C-terminus. This antibody was used on ELISA to test specificity against immunizing peptide. 品种反应性 MonkeyHuman Species Reactivity Note Tested to react with human.
Predicted to react with monkey based on 100% sequence homology.抗体类型 Polyclonal Antibody Entrez基因编号 - NP_060872
Entrez基因汇总 This gene was identified by its overexpression specifically in herpesvirus samimiri-transformed T cells. The encoded protein is a member of the IL10 family of cytokines. It is a secreted protein and may function as a homodimer. This protein is thought to contribute to the transformed phenotype of T cells after infection by herpesvirus samimiri. [provided by RefSeq] 基因符号 - IL-26
- IL26
- AK155
纯化方法 Affinity Purfied UniProt编号 - Q9NPH9
UniProt汇总 SUBUNIT STRUCTURE: Homodimer.
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICITY: Expressed in HVS transformed T-cells but not other T-cell lines or primary stimulated T-cells.
INDUCTION: By Herpesvirus saimiri infection.
SEQUENCE SIMILARITIES: Belongs to the IL-10 family.产品使用声明 质量保证 Evaluated by Western Blot on recombinant human IL-26.
Western Blot Analysis: 0.1 µg/mL of this antibody detected recombinant human IL-26.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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下一件merck millipore产品：merck millipore,默克密理博,70045,pBAC™4x-1 DNA - Novagen
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