merck millipore,默克密理愽
  • merck millipore,默克密理博,06-004,Anti-Secreted frizzled-related protein 2 Antibody

  • merck millipore,默克密理博,06-004,Anti-Secreted frizzled-related protein 2 Antibody

    产品名称：Anti-Secreted frizzled-related protein 2 Antibody
    产品型号：06-004
    Anti-Secreted frizzled-related protein 2 Antibody is an antibody against Secreted frizzled-related protein 2 for use in WB.

    merck millipore,默克密理博,06-004,Anti-Secreted frizzled-related protein 2 Antibody

  • 产品介绍
  • merck millipore,默克密理博,06-004,Anti-Secreted frizzled-related protein 2 Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    Po, M, H, R, Ca, PmWBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 06-004
    描述 Anti-Secreted frizzled-related protein 2 Antibody
    Alternate Names
    • Secreted apoptosis-related protein 1
    • secreted frizzled-related protein 2
    • secreted apoptosis related protein 1
    背景信息 Secreted frizzled-related proteins (SFRPs) may play a critical role in carcinogenesis by inhibiting the Wnt/beta-catenin signaling pathway. Secreted frizzled-related protein 2 may be useful to further investigate mammary tumorigenesis as its expression increases with tumor progression in canine mammary gland tumors. Silencing of Secreted frizzled-related protein 2 in mouse embryos has been found to cause severe shortening of the thoracic region. Studies have shown that this protein is the essential stem cell paracrine factor that is thought to regulate myocardial survival and repair damage in the aftermath of an ischemic injury.
    产品信息
    格式 Affinity Purified
    控制
    • NIH/3T3/L1 adipocytic lysate
    演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Anti-Secreted frizzled-related protein 2 Antibody is an antibody against Secreted frizzled-related protein 2 for use in WB.
    主要应用
    • Western Blotting
    生物信息
    免疫原品种 KLH-conjugated linear peptide corresponding to human Secreted frizzled-related protein 2 corresponding to the C-terminus.
    表位 Corresponding to the C-terminus
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 This antibody recognizes Secreted frizzled-related protein 2 corresponding to the C-terminus.
    品种反应性 PigMouseHumanRatCaninePrimate
    Species Reactivity Note Demonstrated to react with Mouse. Predicted to react with Human, Rat, Canine, Primate, and Porcine based on 100% sequence homology.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NP_003004
    Entrez基因汇总 This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer. [provided by RefSeq].
    基因符号
    • FRP2
    • SFRP2
    • SARP-1
    • SARP1
    • sFRP-2
    • FRP-2
    • SDF-5
    纯化方法 Affinity purified
    UniProt编号
    • Q96HF1
    UniProt汇总 FUNCTION: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis.

    SUBCELLULAR LOCATION: Secreted (By similarity).

    TISSUE SPECIFICITY: Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon.

    DOMAIN: The FZ domain is involved in binding with Wnt ligands (By similarity).

    SEQUENCE SIMILARITIES: Belongs to the secreted frizzled-related protein (sFRP) family.

    Contains 1 FZ (frizzled) domain.

    Contains 1 NTR domain.
    产品使用声明
    质量保证 Evaluated by Western Blot in NIH/3T3/L1 adipocytic lysate.

    Western Blot Analysis: 0.5 µg/mL of this antibody detected Secreted frizzled-related protein 2 on 10 µg of NIH/3T3/L1 adipocytic lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,06-004,Anti-Secreted frizzled-related protein 2 Antibody

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