merck millipore,默克密理博,05-983,Anti-PKC Antibody (α, β, γ), clone M110

搜索"Merck Millipore 密理愽"产品

Merck Millipore 默克密理愽

当前位置：首页 > >Merck Millipore > 生命科学研究
生命科学研究

merck millipore,默克密理博,05-983,Anti-PKC Antibody (α, β, γ), clone M110
产品名称：Anti-PKC Antibody (α, β, γ), clone M110
产品型号：05-983
Anti-PKC (α Antibody, β, γ), clone M110 detects level of PKC (α & has been published & validated for use in ELISA, IP, WB & IC.

merck millipore,默克密理博,05-983,Anti-PKC Antibody (α, β, γ), clone M110

产品介绍

merck millipore,默克密理博,05-983,Anti-PKC Antibody (α, β, γ), clone M110

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
R, H, M	ICC, ELISA, WB	M	Purified	Monoclonal Antibody

描述
产品目录编号	05-983
品牌系列	Upstate
商名	Upstate
描述	Anti-PKC Antibody (α, β, γ), clone M110
Alternate Names	PRKCA, PRKCB, PRKCG, protein kinase C, alpha, beta, gamma beta alpha protein kinase C PRKCG PRKCB PRKCA

产品信息
格式	Purified
演示	100 μL of protein A purified mouse monoclonal IgG1 in 50% affinity storage buffer (PBS containing 1.0 mg/mL BSA and 0.05% sodium azide) and 50% glycerol.

应用
应用	Anti-PKC (α Antibody, β, γ), clone M110 detects level of PKC (α & has been published & validated for use in ELISA, IP, WB & IC.
主要应用	Immunocytochemistry ELISA Western Blotting

生物信息
免疫原品种	Recombinant protein of human PKCγ amino acids 499-697.
克隆	clone M110
宿主	Mouse
特异性	Recognizes PKC α, β, γ. Does not cross react with other PKC isoforms.
同种型	IgG1
品种反应性	RatHumanMouse
抗体类型	Monoclonal Antibody
Entrez基因编号	NP_002728, NP_002730
Entrez基因汇总	Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.
基因符号	PKCA PRKCA PKC-A AAG6 PKC-alpha MGC129901 MGC129900 PRKACA
纯化方法	Protein A purfied
UniProt编号	P05129 P17252 P05771
UniProt汇总	FUNCTION: SwissProt: P17252 # PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. COFACTOR: Binds 3 calcium ions per subunit. The ions are bound to the C2 domain (By similarity). SIZE: 672 amino acids; 76764 Da SUBUNIT: Interacts with CENTA1, CSPG4 and PRKCABP. Binds to SDPR in the presence of phosphatidylserine. SIMILARITY: SwissProt: P17252 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 1 C2 domain. & Contains 2 phorbol-ester/DAG-type zinc fingers. & Contains 1 protein kinase domain.

产品使用声明
质量保证	Routinely evaluated by immunoblot.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 2 years at -20°C from date of shipment. Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol-containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 2 years at -20°C from date of shipment. Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol-containing solutions to become frozen during storage.

包装信息
数量	100 µL

merck millipore,默克密理博,05-983,Anti-PKC Antibody (α, β, γ), clone M110

上一件merck millipore产品：merck millipore,默克密理博,AB10206,Anti-NLK Antibody
下一件merck millipore产品：merck millipore,默克密理博,12-427,Phospho (Ser10)-Histone H3 Peptide, biotin conjugate

merck millipore,默克密理博,234405,Complement C5-Depleted Serum, Human

merck millipore,默克密理博,04-1019,Anti-Synaptophysin (CT) Antibody, clone YE269, rabbit monoclonal

merck millipore,默克密理博,14-911M,Aurora C, active

merck millipore,默克密理博,AB10206,Anti-NLK Antibody

merck millipore,默克密理博,12-427,Phospho (Ser10)-Histone H3 Peptide, biotin conjugate

merck millipore,默克密理博,IM16,Anti-Cathepsin D (Ab-2) Rabbit pAb

merck millipore,默克密理博,559274,S6K1 Inhibitor II, DG2 - Calbiochem

merck millipore,默克密理博,AB1513P,Anti-Brain Derived Neurotrophic Factor Antibody

merck millipore,默克密理博,SF-892,GNAQ; Human, Cyanine 3, RNA Detection Probe,SmartFlare

whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech