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merck millipore,默克密理博,05-909,Anti-AP-2γ Antibody, clone 6E4/4
产品名称：Anti-AP-2γ Antibody, clone 6E4/4
产品型号：05-909
Detect AP-2γ also known as Transcription Factor AP-2 gamma with Anti-AP-2γ Antibody, clone 6E4/4 (Mouse Monoclonal Antibody), that has been demonstrated to work in WB & IHC.
merck millipore,默克密理博,05-909,Anti-AP-2γ Antibody, clone 6E4/4
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M, H IHC, WB M Purified Monoclonal Antibody 描述 产品目录编号 05-909 品牌系列 Upstate
商名 - Upstate
描述 Anti-AP-2γ Antibody, clone 6E4/4 产品信息 格式 Purified 应用 应用 Detect AP-2γ also known as Transcription Factor AP-2 gamma with Anti-AP-2γ Antibody, clone 6E4/4 (Mouse Monoclonal Antibody), that has been demonstrated to work in WB & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
生物信息 免疫原品种 Bacterially expressed AP-2 protein 克隆 clone 6E4/4 宿主 Mouse 特异性 AP-2γ. Reported to not cross-react with AP-2α or AP-2β. 同种型 IgG 品种反应性 MouseHuman 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_003222.3
Entrez基因汇总 The protein encoded by this gene is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The encoded protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation. It plays a role in the development of the eyes, face, body wall, limbs, and neural tube. 基因符号 - ERF1
- TFAP2C
- AP2-GAMMA
- TFAP2G
- hAP-2g
- AP2-gamma
纯化方法 Protein G purfied UniProt编号 - Q92754
UniProt汇总 FUNCTION: SwissProt: Q92754 # Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.
SIZE: 450 amino acids; 49177 Da
SUBUNIT: Binds DNA as a dimer. Can form homodimers or heterodimers with other AP-2 family members (By similarity). Interacts with WWOX. Interacts with CITED4. Interacts with UBE2I.
SUBCELLULAR LOCATION: Nucleus (Probable).
DOMAIN:SwissProt: Q92754 The WW-binding motif mediates interaction with WWOX.
PTM: Sumoylated on Lys-10; which inhibits transcriptional activity.
SIMILARITY: Belongs to the AP-2 family.产品使用声明 质量保证 routinely evaluated by immunoblot on nuclear extracts from HeLa cells 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 stable 2 years at -20°C from date of shipment 包装信息 数量 100 µg
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