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品种反应性 主要应用 宿主 格式 抗体类型 R, H, M WB M Purified Monoclonal Antibody 描述 产品目录编号 05-850 品牌系列 Upstate
商名 - Upstate
描述 Anti-p68 Antibody, clone204 概述 Also known as DDX5, p68 is a DEAD-box ATPase and RNA splicing factor. 产品信息 格式 Purified 应用 应用 Detect p68 with Anti-p68 Antibody, clone204 (Mouse Monoclonal Antibody), that has been shown to work in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 Purified T antigen-related protein from Ad2+ ND2 virus-infected HeLa cells. 克隆 clone204 宿主 Mouse 特异性 p68 同种型 IgG1 品种反应性 RatHumanMouse 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_004396
Entrez基因汇总 DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a RNA-dependent ATPase, and also a proliferation-associated nuclear antigen, specifically reacting with the simian virus 40 tumor antigen. This gene consists of 13 exons, and alternatively spliced transcripts containing several intron sequences have been detected, but no isoforms encoded by these transcripts have been identified. 基因符号 - G17P1
- DDX5
- HUMP68
- DKFZp686J01190
- p68
- HLR1
- HELR
纯化方法 Protein G purfied UniProt编号 - P17844
UniProt汇总 FUNCTION: SwissProt: P17844 # RNA-dependent ATPase activity. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. May be involved in pre-mRNA splicing.
SIZE: 614 amino acids; 69148 Da
SUBUNIT: Identified in the spliceosome C complex, at least composed of AQR, ASCC3L1, C19orf29, CDC40, CDC5L, CRNKL1, DDX23, DDX41, DDX48, DDX5, DGCR14, DHX35, DHX38, DHX8, EFTUD2, FRG1, GPATC1, HNRPA1, HNRPA2B1, HNRPA3, HNRPC, HNRPF, HNRPH1, HNRPK, HNRPM, HNRPR, HNRPU, KIAA1160, KIAA1604, LSM2, LSM3, MAGOH, MORG1, PABPC1, PLRG1, PNN, PPIE, PPIL1, PPIL3, PPWD1, PRPF19, PRPF4B, PRPF6, PRPF8, RALY, RBM22, RBM8A, RBMX, SART1, SF3A1, SF3A2, SF3A3, SF3B1, SF3B2, SF3B3, SFRS1, SKIV2L2, SNRPA1, SNRPB, SNRPB2, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, SNRPG, SNW1, SRRM1, SRRM2, SYF2, SYNCRIP, TFIP11, THOC4, U2AF1, WDR57, XAB2 and ZCCHC8.
SUBCELLULAR LOCATION: Nucleus, nucleolus.
PTM: Arg-502 is dimethylated, probably to asymmetric dimethylarginine.
SIMILARITY: SwissProt: P17844 ## Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily. & Contains 1 helicase ATP-binding domain. & Contains 1 helicase C-terminal domain.产品使用声明 质量保证 Routinely evaluated by immunoblot of nuclear extracts from HeLa cells 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 200 µg
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