merck millipore,默克密理愽
  • merck millipore,默克密理博,05-779,Anti-Meis 1/2/3 Antibody, clone 9.2.7

  • merck millipore,默克密理博,05-779,Anti-Meis 1/2/3 Antibody, clone 9.2.7

    产品名称：Anti-Meis 1/2/3 Antibody, clone 9.2.7
    产品型号：05-779
    Detect Meis 1/2/3 with Anti-Meis 1/2/3 Antibody, clone 9.2.7 (Mouse Monoclonal Antibody), that has been shown to work in IP, WB & IHC.

    merck millipore,默克密理博,05-779,Anti-Meis 1/2/3 Antibody, clone 9.2.7

  • 产品介绍
  • merck millipore,默克密理博,05-779,Anti-Meis 1/2/3 Antibody, clone 9.2.7

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    M, HIHC, WBMAscitesMonoclonal Antibody
    描述
    产品目录编号 05-779
    Replaces MABN1071
    品牌系列 Upstate
    商名
    • Upstate
    描述 Anti-Meis 1/2/3 Antibody, clone 9.2.7
    背景信息 Hox, Pbx, and Meis families of transcription factors form heteromeric complexes and bind DNA through specific homeobox domains. Meis1, 2, and 3 are members of the TALE (three amino acid loop extension) family of homeodomain containing proteins. Meis1 binds to Hox and Pbx proteins to form complexes with distinct DNA-binding specificities. Like Hox and Pbx proteins, the overexpression of Meis1 in BHX-2 myeloid leukemias implies a role for this protein in oncogenesis. Two Meis related proteins, Meis2 and Meis3 (also designated Mrg1 and Mrg2, respectively), possess largely similar sequence identity with Meis1 and express in normal tissues as well as myeloid leukemias. In the pancreas, Meis2 preferentially associates with Pbx1, and together they associate with the pancreas specific homeodomain factor, Pdx1, to repress Pdx1-induced transcriptional activation.
    产品信息
    格式 Ascites
    控制
    • K562 nuclear extract
    演示 mouse ascites IgG1 containing 0.05% sodium azide before the addition of glycerol to 30%
    应用
    应用 Detect Meis 1/2/3 with Anti-Meis 1/2/3 Antibody, clone 9.2.7 (Mouse Monoclonal Antibody), that has been shown to work in IP, WB & IHC.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    生物信息
    免疫原品种 MBP-conjugated fusion protein corresponding to amino acids 60-390 of mouse Meis1
    克隆 clone 9.2.7
    宿主 Mouse
    特异性 Meis1, Meis2, Meis3 and splice variants
    同种型 IgG1
    品种反应性 MouseHuman
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_170677
    Entrez基因汇总 This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. TALE homeobox proteins are highly conserved transcription regulators, and several members have been shown to be essential contributors to developmental programs. Multiple transcript variants encoding distinct isoforms have been described for this gene.
    基因符号
    • HsT18361
    • MEIS2
    • MGC2820
    • MRG1
    纯化方法 Ascites
    UniProt编号
    • O14770
    UniProt汇总 SIZE: 477 amino acids; 51790 Da
    SUBCELLULAR LOCATION: Nucleus (Probable).
    TISSUE SPECIFICITY: Expressed in various tissues. In hematopoietic tissues, the lymphoid organs express high levels of MEIS2. Also expressed in some regions of the brain, such as the putamen.
    SIMILARITY: SwissProt: O14770 ## Belongs to the TALE/MEIS homeobox family. & Contains 1 homeobox DNA-binding domain.
    产品使用声明
    质量保证 routinely evaluated by immunoblot on nuclear extract from K562 cells
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 2 years at -20°C
    包装信息
    数量 100 µL

    merck millipore,默克密理博,05-779,Anti-Meis 1/2/3 Antibody, clone 9.2.7

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