merck millipore,默克密理愽
  • merck millipore,默克密理博,05-762,Anti-Caveolin-1 Antibody, clone 7C8

  • merck millipore,默克密理博,05-762,Anti-Caveolin-1 Antibody, clone 7C8

    产品名称：Anti-Caveolin-1 Antibody, clone 7C8
    产品型号：05-762
    Anti-Caveolin-1 Antibody, clone 7C8 detects level of Caveolin-1 & has been published & validated for use in IC, IP & WB.

    merck millipore,默克密理博,05-762,Anti-Caveolin-1 Antibody, clone 7C8

  • 产品介绍
  • merck millipore,默克密理博,05-762,Anti-Caveolin-1 Antibody, clone 7C8

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, HWB, ICCMPurifiedMonoclonal Antibody
    描述
    产品目录编号 05-762
    品牌系列 Upstate
    商名
    • Upstate
    描述 Anti-Caveolin-1 Antibody, clone 7C8
    产品信息
    格式 Purified
    演示 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
    应用
    应用 Anti-Caveolin-1 Antibody, clone 7C8 detects level of Caveolin-1 & has been published & validated for use in IC, IP & WB.
    主要应用
    • Western Blotting
    • Immunocytochemistry
    生物信息
    免疫原品种 Intracellular membrane protein-containing vesicles (containing GLUT4) from rat adipocytes
    克隆 clone 7C8
    宿主 Mouse
    特异性 caveolin-1α and caveolin-1β
    同种型 IgG2b
    品种反应性 RatHuman
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_001753
    Entrez基因汇总 The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene.
    基因符号
    • VIP21
    • CAV1
    • MSTP085
    • Caveolin-1.
    • CAV
    纯化方法 Protein A purfied
    UniProt编号
    • Q03135
    UniProt汇总 FUNCTION: SwissProt: Q03135 # May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity).
    SIZE: 178 amino acids; 20472 Da
    SUBUNIT: Homooligomer. Interacts with GLIPR2, NOSTRIN, SNAP25 and syntaxin.
    SUBCELLULAR LOCATION: Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane, caveola; Peripheral membrane protein; Cytoplasmic side. Note=Membrane protein of caveolae. Potential hairpin-like structure in the membrane.
    TISSUE SPECIFICITY: In muscle and lung, less so in liver, brain and kidney.
    PTM: The initiator methionine for isoform Beta is removed during or just after translation. The new N-terminal amino acid is then N-acetylated.
    SIMILARITY: SwissProt: Q03135 ## Belongs to the caveolin family.
    产品使用声明
    质量保证 routinely evaluated by immunoblot on RIPA lysates from A431 cells
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 2 years at -20°C
    包装信息
    数量 200 µg

    merck millipore,默克密理博,05-762,Anti-Caveolin-1 Antibody, clone 7C8

上一件merck millipore产品：merck millipore,默克密理博,AB3381,Anti-Myosin Light Chain Antibody, phospho-specific (Ser19)
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