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品种反应性 主要应用 宿主 格式 抗体类型 R, H, M WB M Purified Monoclonal Antibody 描述 产品目录编号 05-639 品牌系列 Upstate
商名 - Upstate
描述 Anti-14-3-3γ Antibody, clone CG31-2B6 产品信息 格式 Purified 演示 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30% 应用 应用 This Anti-14-3-3γ Antibody, clone CG31-2B6 is validated for use in WB for the detection of 14-3-3γ. 主要应用 - Western Blotting
生物信息 免疫原品种 GST fusion protein corresponding to full-length human 14-3-3 gamma 克隆 CG31-2B6 宿主 Mouse 特异性 14-3-3 gamma; does not cross-react with other 14-3-3 isoforms 同种型 IgG1 品种反应性 RatHumanMouse 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_012479
Entrez基因汇总 This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways. 基因符号 - 14-3-3GAMMA
- YWHAG
- KCIP-1
纯化方法 Protein A chromatography UniProt编号 - P61981
UniProt汇总 FUNCTION: SwissProt: P61981 # Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
SIZE: 247 amino acids; 28303 Da
SUBUNIT: Homodimer. Interacts with RAF1 and SSH1.
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
TISSUE SPECIFICITY: Highly expressed in brain, skeletal muscle, and heart.
PTM: Phosphorylated by various PKC isozymes.
SIMILARITY: SwissProt: P61981 ## Belongs to the 14-3-3 family.产品使用声明 质量保证 routinely evaluated by immunoblot on RIPA lysate from 3T3/A31 cells 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,565190,Serum Amyloid P Component, Human Serum
下一件merck millipore产品：merck millipore,默克密理博,14-683,PAK3 Protein, active, 10 µg
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