merck millipore,默克密理博,04-342,Anti-phospho-eIF-2α (Ser51) Antibody, rabbit monoclonal

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merck millipore,默克密理博,04-342,Anti-phospho-eIF-2α (Ser51) Antibody, rabbit monoclonal
产品名称：Anti-phospho-eIF-2α (Ser51) Antibody, rabbit monoclonal
产品型号：04-342
Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target. This Anti-phospho-eIF-2α (Ser51) Antibody, rabbit is More>>

merck millipore,默克密理博,04-342,Anti-phospho-eIF-2α (Ser51) Antibody, rabbit monoclonal

产品介绍

merck millipore,默克密理博,04-342,Anti-phospho-eIF-2α (Ser51) Antibody, rabbit monoclonal

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
R, H, M	WB, ICC	Rb	Purified	Monoclonal Antibody

描述
产品目录编号	04-342
品牌系列	Upstate
商名	Upstate
描述	Anti-phospho-eIF-2α (Ser51) Antibody, rabbit monoclonal
Alternate Names	EIF-2A

产品信息
格式	Purified
演示	100 μL of rabbit monoclonal IgG in 30 mM Tris-Glycine (pH 7.4), 90 mM NaCl, 0.006% sodium azide, 0.03% BSA and 40% glycerol.

应用
应用	Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target. This Anti-phospho-eIF-2α (Ser51) Antibody, rabbit is validated for use in IC, IH(P), WB for the detection of phospho-eIF-2α (Ser51).
主要应用	Western Blotting Immunocytochemistry
应用说明	Suggested Dilutions: Immunoblot Analysis: 1:1,000 Immunocytochemistry: 1:100 - 1:250 Immunohistochemistry: 1:50-1:100

生物信息
免疫原品种	KLH-conjugated synthetic phospho-peptide corresponding to residues surrounding Ser51 of human eIF-2α
宿主	Rabbit
特异性	Recognizes the eIF-2α when phosphorylated on Ser51.
同种型	IgG
品种反应性	RatHumanMouse
抗体类型	Monoclonal Antibody
Entrez基因编号	NM_032025.3
Entrez基因汇总	EIF2A is a 65-kD protein that catalyzes the formation of puromycin-sensitive 80S preinitiation complexes (Zoll et al., 2002 [PubMed 12133843]).[supplied by OMIM]
基因符号	CDA02 EIF2A eIF-2A MSTP089 MSTP004 MST089 EIF-2A ORFNames=CDA02
修改	Phosphorylation
纯化方法	Serum
UniProt编号	Q9BY44
UniProt汇总	FUNCTION: SwissProt: Q9BY44 # Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF- 2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon- dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins. SIZE: 585 amino acids; 64976 Da TISSUE SPECIFICITY: Widely expressed. Expressed at higher level in pancreas, heart, brain and placenta. SIMILARITY: SwissProt: Q9BY44 ## Belongs to the WD repeat EIF2A family. & Contains 3 WD repeats.

产品使用声明
质量保证	Routinely evaluated by immunoblot.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	2 years at -20°C from date of shipment. Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol-containing solutions to become frozen during storage.

储存和货运信息

存储条件

2 years at -20°C from date of shipment.
Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol-containing solutions to become frozen during storage.