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主要应用 Protein Binding 描述 产品目录编号 03-207 品牌系列 Upstate
商名 - Upstate
描述 Chloroethyl Ubiquitin (HA-tag) 背景信息 The ubiquitin cascade in its many forms includes a large family of cysteine proteases known as deubiquitinylating enzymes (DUBs). Many members are assigned to this enzyme class by sequence similarity but with little evidence for specific biological activity. HA-tagged ubiquitin molecules derivatised by chemical ligation at the C-terminus with thiol-reactive functional groups can be used as potent, irreversible inhibitors of DUBs through their covalent modification of the active site and, consequently, can act as specific probes for enzymes with DUB activity. Such probes have been utilized for the identification of DUBs and associated components from cell lysates by proteomic methods, as well as rapid demonstration of enzymatic activity for gene products whose functions were inferred from primary structure. The nature of the electrophilic group used as the C-terminal derivative, for example vinyl sulfone (-VS), vinyl methylester (-VME), 2-bromoethyl (-Br) or 2-chloroethyl (-Cl), may determine the subset of DUB enzymes detected. 产品信息 格式 Purified 演示 Lyophilized;reconstitute with aqueous buffer up to 5 mg/mL (~500 µM) 应用 主要应用 - Protein Binding
生物信息 纯度 >95% by HPLC 来源 Synthetic peptide 物理形式 Frozen solution 纯化方法 HPLC 产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 After opening, prepare aliquots and store at -80ºC. Avoid freeze/thaw cycles. After reconstitution, prepare aliquots, store at -80ºC and use within 1 month. Stable for at least 6 months after receipt when stored at -80ºC. 包装信息 数量 25 µg
上一件merck millipore产品：merck millipore,默克密理博,196872,BAY 11-7085 - CAS 196309-76-9 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,70956,Rosetta™(DE3)pLysS Competent Cells - Novagen
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