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merck millipore,默克密理博,SF-167,VEGF; Human, Cyanine 3, RNA Detection Probe,SmartFlare
产品名称：VEGF; Human, Cyanine 3, RNA Detection Probe, SmartFlare
产品型号：SF-167
Use SmartFlare RNA Detection probes to measure gene expression in live cells. With an overnight incubation of SmartFlare VEGF, Human, Cyanine 3, you can detect VEGF RNA levels within your cells.
merck millipore,默克密理博,SF-167,VEGF; Human, Cyanine 3, RNA Detection Probe,SmartFlare
- 产品介绍
重要规格表
Entrez Gene Number Species Reactivity Species Reactivity Note NM_003376.5 H NM_001025366.2, NM_001025367.2, NM_001025368.2, NM_001025369.2, NM_001025370.2, NM_001033756.2, NM_001171622.1, NM_001204384.1 描述 产品目录编号 SF-167 商名 - SmartFlare
描述 VEGF; Human, Cyanine 3, RNA Detection Probe | SmartFlare Alternate Names - MVCD1
- VEGFA
- VPF
背景信息 With SmartFlare™ RNA Detection probes, you can detect RNA in LIVE CELLS with ease. With just an overnight incubation of VEGF; Human, Cyanine 3, RNA Detection Probe you can detect the presence of VEGF within your cells.
VEGF (Vascular endothelial growth factor, VEGFA, VEGF-A), a dimeric ligand, is among the most potent angiogenic mitogens. VEGF is secreted by tumor cells and other cells exposed to hypoxia. VEGF is a highly specific mitogen for vascular endothelial cells. Seven VEGF isoforms (a, b, c, d, e, f, g) are generated as a result of alternative splicing from a single VEGF gene. The most commonly studied isoforms are VEGF121, VEGF165, and VEGF189 (f, d and b, respectively) All seven isoforms differ in their molecular mass and in biological properties such as their ability to bind to cell-surface heparan-sulfate proteoglycans. The expression of VEGF is potentiated and is secreted by tumor cells in response to hypoxia, by activated oncogenes, and by a variety of cytokines. VEGF induces angiogenesis as well as permeabilization of blood vessels, and plays a central role in the regulation of vasculogenesis. VEGF expression correlates to the degree of tumor vascularization and with increased metastatic risk. Additionally, VEGF induces endothelial cell proliferation, promotes cell migration, and inhibits apoptosis. Consequently, inhibition of VEGF signaling abrogates the development of a wide variety of tumors.产品信息 格式 Cyanine 3 演示 Lyophilized 应用 应用 Use SmartFlare RNA Detection probes to measure gene expression in live cells. With an overnight incubation of SmartFlare VEGF, Human, Cyanine 3, you can detect VEGF RNA levels within your cells. 主要应用 - RNA Detection
生物信息 品种反应性 Human Species Reactivity Note NM_001025366.2, NM_001025367.2, NM_001025368.2, NM_001025369.2, NM_001025370.2, NM_001033756.2, NM_001171622.1, NM_001204384.1 Entrez基因编号 - NM_003376.5
基因符号 - VEGF
产品使用声明 质量保证 SmartFlare Probes have been tested in a buffer system to detect the release of the fluorophore in the presence of a complimentary base pair sequence for each lot to confirm target specificity. SmartFlare Probes have also been tested in a cell model system and demonstrated increased fluorescence in cells expressing the target compared to a negative SmartFlare Scramble Control. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Store at 2–8°C in lyophilized format ONLY. Room temperature is required for reconstituted product. 包装信息 数量 250 reactions
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