merck millipore,默克密理愽
  • merck millipore,默克密理博,MABT95,Anti-Arp2/3 complex Antibody, clone 13C9

  • merck millipore,默克密理博,MABT95,Anti-Arp2/3 complex Antibody, clone 13C9

    产品名称：Anti-Arp2/3 complex Antibody, clone 13C9
    产品型号：MABT95
    Anti-Arp2/3 complex Antibody, clone 13C9 detects level of Arp2/3 complex & has been published & validated for use in WB, IH(P).

    merck millipore,默克密理博,MABT95,Anti-Arp2/3 complex Antibody, clone 13C9

  • 产品介绍
  • merck millipore,默克密理博,MABT95,Anti-Arp2/3 complex Antibody, clone 13C9

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HWBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABT95
    描述 Anti-Arp2/3 complex Antibody, clone 13C9
    Alternate Names
    • p21-ARC
    • Actin-related protein 2/3 complex subunit 3
    • Arp2/3 complex 21 kDa subunit
    背景信息 The Arp2/3 complex, which contains ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC, plays a major role in the regulation of the actin polymerization in the cytoskeleton. Two of complex's seven subunits (ARP2 and ARP3) closely resemble monomeric actin and serve as nucleation sites for new actin filaments. The Arp2/3 complex works in conjunction with an activating nucleation-promoting factor (NPF) to aid in the formation of branched actin networks. The regulation of actin cytoskeleton reorganization is important for processes like cell migration, phagocytosis, and intracellular motility of lipid vesicles.
    产品信息
    格式 Purified
    控制
    • MCF-7 cell lysate
    演示 Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Anti-Arp2/3 complex Antibody, clone 13C9 detects level of Arp2/3 complex & has been published & validated for use in WB, IH(P).
    主要应用
    • Western Blotting
    应用说明 Immunohistochemistry Analysis: A 1:5,000 dilution from a representative lot detected Arp2/3 complex in human colorectal cancer and human colon tissues (antibody may need further dilution if staining is too strong - optimal dilution to be determined by the end user).
    生物信息
    免疫原品种 GST-tagged recombinant protein corresponding to human Arp2/3 complex.
    克隆 13C9
    宿主 Mouse
    同种型 IgG2aκ
    品种反应性 Human
    Species Reactivity Note Demonstrated to react with Human.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_005710
    Entrez基因汇总 This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p21 subunit, has yet to be determined. [provided by RefSeq, Jul 2008].
    基因符号
    • ARC21
    • ARPC3
    纯化方法 Protein G purified
    UniProt编号
    • O15145
    UniProt汇总 FUNCTION: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.

    SUBUNIT STRUCTURE: Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC.

    SUBCELLULAR LOCATION: Cytoplasm › cytoskeleton. Cell projection

    SEQUENCE SIMILARITIES: Belongs to the ARPC3 family.
    产品使用声明
    质量保证 Evaluated by Western Blot in MCF-7 cell lysate.

    Western Blot Analysis: A 1:5,000 dilution of this antibody detected Arp2/3 complex on 10 µg of MCF-7 cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,MABT95,Anti-Arp2/3 complex Antibody, clone 13C9

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