merck millipore,默克密理博,MABT381,Anti-Alpha-Actin (smooth muscle) Antibody, clone EPR5368, rabbit monoclonal

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merck millipore,默克密理博,MABT381,Anti-Alpha-Actin (smooth muscle) Antibody, clone EPR5368, rabbit monoclonal
产品名称：Anti-Alpha-Actin (smooth muscle) Antibody, clone EPR5368, rabbit monoclonal
产品型号：MABT381
Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target.

merck millipore,默克密理博,MABT381,Anti-Alpha-Actin (smooth muscle) Antibody, clone EPR5368, rabbit monoclonal

产品介绍

merck millipore,默克密理博,MABT381,Anti-Alpha-Actin (smooth muscle) Antibody, clone EPR5368, rabbit monoclonal

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
R, H, M	FC, ICC	Rb	Unpurified	Monoclonal Antibody

描述
产品目录编号	MABT381
描述	Anti-Alpha-Actin (smooth muscle) Antibody, clone EPR5368, rabbit monoclonal
Alternate Names	Alpha-actin-2 actin, alpha 2, smooth muscle, aorta Cell growth-inhibiting gene 46 protein actin, aortic smooth muscle alpha 2 actin alpha-actin-2 alpha-cardiac actin growth-inhibiting gene 46
背景信息	Actins are highly conserved proteins ubiquitously expressed in all eukaryotic cells. They comprise, along with microtubules, a major component of the cytoskeleton. Actin has been found to be expressed in at least six isomeric forms. It is expressed in heart and skeletal striated muscle tissue, and in certain smooth muscle tissues, regulating contractile potentials for these cells. It is also expressed in the cytoplasm of non-muscle cells, functioning to control cell structure and motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin), whose formation requires the Arp2/3 complex. It has been reported that actin is hyperphosphorylated in primary breast tumors. It has also been shown that actin dysfunction leads to certain types of heart failure. Smooth muscle alpha actin is of further interest because it is one of a few genes whose expression is relatively restricted to vascular smooth muscle cells. Furthermore, expression of smooth muscle alpha actin is regulated by hormones and cell proliferation, and is altered by pathological conditions including oncogenic transformation and atherosclerosis.

产品信息
格式	Unpurified
控制	Human heart tissue lysate
演示	Rabbit Monoclonal in buffer containing glycerol, BSA, and sodium azide.

应用
应用	Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target.
主要应用	Flow Cytometry Immunocytochemistry
应用说明	Immunohistochemistry Analysis: A 1:1,000-2,500 dilution from a representative lot was used to detect Alpha Actin in human ovary tissue. Immunocytochemistry Analysis: A 1:250-500 dilution from a representative lot was used in IC. Flow Cytometry Analysis: A 1:10-100 dilution from a representative lot was used in FC.

生物信息
免疫原品种	Synthetic peptide corresponding to the N-terminus of human Alpha Actin.
表位	N-terminus
克隆	EPR5368
宿主	Rabbit
特异性	This antibody recognizes the N-terminus of Alpha Actin.
品种反应性	RatHumanMouse
Species Reactivity Note	Demonstrated to react with Human, Rat, and Mouse.
抗体类型	Monoclonal Antibody
Entrez基因编号	P62736
基因符号	ACTVS ACTSA AAT6 OTTHUMP00000020042
纯化方法	Unpurified
UniProt编号	P62736

产品使用声明
质量保证	Evaluated by Immunohistochemistry on human heart tissue lysate. Immunohistochemistry Analysis: A 1:1,000-2,500 dilution of this antibody was used to detect Alpha Actin in human heart tissue.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20ºC from date of receipt. Handling Recommendations: Upon first thaw, and prior to removing cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20ºC. Avoid freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20ºC from date of receipt.
Handling Recommendations: Upon first thaw, and prior to removing cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20ºC. Avoid freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.