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merck millipore,默克密理博,MABS395,Anti-Monoglyceride Lipase Antibody, clone EPR6339, rabbit monoclonal
产品名称:Anti-Monoglyceride Lipase Antibody, clone EPR6339, rabbit monoclonal
产品型号:MABS395
Detect Monoglyceride lipase using this rabbit monoclonal antibody, Anti-Monoglyceride Lipase Antibody & clone EPR6339 validated for use in western blotting.
merck millipore,默克密理博,MABS395,Anti-Monoglyceride Lipase Antibody, clone EPR6339, rabbit monoclonal
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Unpurified Monoclonal Antibody 描述 产品目录编号 MABS395 描述 Anti-Monoglyceride Lipase Antibody, clone EPR6339, rabbit monoclonal Alternate Names - MAGL
- Monoglyceride lipase
- MGL
- HU-K5
- Lysophospholipase homolog
- Lysophospholipase-like
- Monoacylglycerol lipase
背景信息 Monoglyceride lipase (MGL), or alternatively HU-K5, Lysophospholipase homolog, Lysophospholipase-like, or Monoacylglycerol lipase (MAGL) is a protein encoded by the MGLL gene in humans and is very important in lipid metabolism. Monoglyceride lipase is the enzyme that converts monoacylglycerides (key building blocks of lipids) into free fatty acid chains and glycerol. Also, Monoglyceride Lipase hydrolyzes endocannabinoids which ultimately can regulate nociperception and the perception of pain, so the enzyme is being studied in pain mediation therapies. Monoglyceride Lipase is expressed in many tissues including fat, lung, liver, brain and heart. In disease, Monoglyceride Lipase is being studied most intensely in cancer research. In some cancers it appears to be play a suppressive role in regulating AKT mediated signaling, but in others, since the enzyme regulates the levels of fatty acids that can serve as intra and intercellular signaling molecules, Monoglyceride lipase activity seems to promote cancer cell migration, invasion and growth. EMD-Millipore’s Anti-Monoglyceride Lipase rabbit monoclonal antibody has been tested in western blot on human heart and adipose tissue lysates. 产品信息 格式 Unpurified 控制 - Human heart tissue lysate
演示 Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol. 应用 应用 Detect Monoglyceride lipase using this rabbit monoclonal antibody, Anti-Monoglyceride Lipase Antibody & clone EPR6339 validated for use in western blotting. 主要应用 - Western Blotting
应用说明 Western Blotting Analysis: A 1:1,000-10,000 dilution from a representative lot detected Monoglyceride Lipase in human adipose tissue lysate.
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Synthetic peptide corresponding to human Monoglyceride Lipase. 克隆 EPR6339 宿主 Rabbit 品种反应性 Human 抗体类型 Monoclonal Antibody 基因符号 - MGLL
纯化方法 Unpurified UniProt编号 - Q99685
产品使用声明 质量保证 Evaluated by Western Blotting in human heart tissue lysate.
Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected Monoglyceride Lipase in human heart tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 100 µL
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