merck millipore,默克密理愽
  • merck millipore,默克密理博,MABS102,Anti-Apolipoprotein H Antibody

  • merck millipore,默克密理博,MABS102,Anti-Apolipoprotein H Antibody

    产品名称：Anti-Apolipoprotein H Antibody
    产品型号：MABS102
    Anti-Apolipoprotein H Antibody detects level of Apolipoprotein H & has been published & validated for use in WB, IH.

    merck millipore,默克密理博,MABS102,Anti-Apolipoprotein H Antibody

  • 产品介绍
  • merck millipore,默克密理博,MABS102,Anti-Apolipoprotein H Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    M, H, RIHC, WBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABS102
    描述 Anti-Apolipoprotein H Antibody
    Alternate Names
    • Beta(2)GPI
    • Beta-2-glycoprotein 1
    • APC inhibitor
    • Activated protein C-binding protein
    • Anticardiolipin cofactor
    • Apolipoprotein H
    • Apo-H<br />Beta-2-glycoprotein I
    • B2GPI
    背景信息 Also known as Native β2-glycoprotein 1, Apolipoprotein H is a carbohydrate-rich plasma protein which is partially comprised of sialylated and galactosylated bi- and triantennary oligosaccharides and is expressed by the liver and secreted in plasma. It is reported that Apolipoprotein H is an initiating antigen that is required for antibody recognition and is also known to bind to anionic phospholipids. It is also suggested to play a role in lipid metabolism.
    产品信息
    格式 Purified
    控制
    • Human liver tissue
    演示 Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Anti-Apolipoprotein H Antibody detects level of Apolipoprotein H & has been published & validated for use in WB, IH.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    应用说明 Western Blot Analysis: 1 µg/mL from a representative lot detected Apolipoprotein H in human liver tissue lysate.
    生物信息
    免疫原品种 GST-Tagged-recombinant protein corresponding to human Apolioprotein H.
    克隆 17D11.1
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    同种型 IgG2aκ
    品种反应性 MouseHumanRat
    Species Reactivity Note Demonstrated to react with Human, Mouse, and Rat.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_000033
    Entrez基因汇总 Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections.
    基因符号
    • B2G1
    • APOH
    纯化方法 Protein G purified
    UniProt编号
    • P02749
    UniProt汇总 FUNCTION: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.

    SUBCELLULAR LOCATION: Secreted.

    TISSUE SPECIFICITY: Expressed by the liver and secreted in plasma.
    产品使用声明
    质量保证 Evaluated by Immunohistochemistry in human liver tissue.

    Immunohistochemistry Analysis: A 1:2,000 dilution of this antibody detected Apolipoprotein H in human liver tissue.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MABS102,Anti-Apolipoprotein H Antibody

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