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品种反应性 主要应用 宿主 格式 抗体类型 M, R WB M Purified Monoclonal Antibody 描述 产品目录编号 MABN93 描述 Anti-MICAL-1 Antibody, clone M1 Alternate Names - MIRab13
- MICAL-like protein 1
- Molecule interacting with Rab13
背景信息 MICAL-1 (Molecule Interacting with CasL 1) is a cytoskeletal regulator that links CasL to intermediate filaments. It interacts with rab1 and is associated with the Golgi apparatus and the intermediate filament cytoskeleton. MICAL-1 seems to play a part in semaphorin signaling to their plexin receptors which control morphological changes through F-actin reorganization. 产品信息 格式 Purified 控制 - C2C12 cell lysate
演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 This Anti-MICAL-1 Antibody, clone M1 is validated for use in WB for the detection of MICAL-1. 主要应用 - Western Blotting
应用说明 Western Blot Analysis: 0.5 µg/mL from a representative lot detected MICAL-1 on 10 µg of rat skeletal muscle tissue lysate. 生物信息 免疫原品种 GST-tagged recombinant protein corresponding to mouse MICAL-1. 克隆 M1 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG2aκ 品种反应性 MouseRat Species Reactivity Note Demonstrated to react with Rat and Mouse. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_803412
基因符号 - Mirab13
- Micall1
- D15Mit260
纯化方法 Protein G UniProt编号 - Q8BGT6
UniProt汇总 FUNCTION: May be a cytoskeletal regulator.
SUBUNIT STRUCTURE: Binds to Rab13 (By similarity).
SUBCELLULAR LOCATION: Cytoplasm › cytoskeleton (By similarity).
SEQUENCE SIMILARITIES: Contains 1 CH (calponin-homology) domain.
Contains 1 LIM zinc-binding domain.
SEQUENCE CAUTION: The sequence BAC98229.1 differs from that shown. Reason: Erroneous initiation.产品使用声明 质量保证 Evaluated by Western Blot in C2C12 cell lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected MICAL-1 on 10 µg of C2C12 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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