merck millipore,默克密理愽
  • merck millipore,默克密理博,MABN531,Anti-Glypican-6 Antibody, clone 6A7.1

  • merck millipore,默克密理博,MABN531,Anti-Glypican-6 Antibody, clone 6A7.1

    产品名称：Anti-Glypican-6 Antibody, clone 6A7.1
    产品型号：MABN531
    Detect Glypican using this mouse monoclonal antibody, Anti-Glypican-6 Antibody, clone 6A7.1 validated for use in western blotting & IHC.

    merck millipore,默克密理博,MABN531,Anti-Glypican-6 Antibody, clone 6A7.1

  • 产品介绍
  • merck millipore,默克密理博,MABN531,Anti-Glypican-6 Antibody, clone 6A7.1

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    H, MIHC, WBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABN531
    描述 Anti-Glypican-6 Antibody, clone 6A7.1
    Alternate Names
    • Secreted glypican-6
    • Glypican-6
    背景信息 The protein named Glypican-6 and encoded by the gene GPC6, is a cell surface membrane proteoglycan protein that contains heparan sulfate residues and appears to act as a cellular receptor for various growth factors, ECM proteins, and enzymes. Moreover, Glypican-6 when over expressed enhances the migration and invasion of many cancer cells through the direct activation of the WNT5A signaling pathway. Additionally, Glypican-6 serves a developmental function as it is highly expressed in fetal tissues and defects give rises to severe dysmorphism and congenital defects. Glypican-6 is widely expressed in critical fetal tissues from kidney to brain, and in the adult high expression is seen in ovary, kidney, intestines and liver, and abundant in many cancer cells. Defects in Glypican-6 are associated with Omodysplasia 1 a rare autosomal recessive skeletal dysplasia characterized by facial dysmorphism and severe congenital micromelia giving club-like appearance to hands and feet.
    产品信息
    格式 Purified
    演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Detect Glypican using this mouse monoclonal antibody, Anti-Glypican-6 Antibody, clone 6A7.1 validated for use in western blotting & IHC.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    应用说明 Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected Glypican-6 in human ovarian follicles and human oviduct tissue.
    生物信息
    免疫原品种 GST-tagged recombinant protein corresponding to human Glypican-6.
    克隆 6A7.1
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 Should detect both pro and secreted for Glypican-6 by immunogen design
    同种型 IgG1κ
    品种反应性 HumanMouse
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_005699
    基因符号
    • UNQ369/PRO705
    • GPC6
    纯化方法 Protein G purified
    UniProt编号
    • Q9Y625
    产品使用声明
    质量保证 Evaluated by Western Blotting in mouse liver tissue lysate.

    Western Blotting Analysis: 1.0 µg/mL of this antibody detected Glypican-6 in 10 µg of mouse liver tissue lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MABN531,Anti-Glypican-6 Antibody, clone 6A7.1

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下一件merck millipore产品：merck millipore,默克密理博,07-1408,Anti-Glucose Regulating Protein 94 (GRP94) Antibody


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