merck millipore,默克密理愽
  • merck millipore,默克密理博,MABN390,Anti-Sigma IR Antibody, clone ICR-SIG1R-A

  • merck millipore,默克密理博,MABN390,Anti-Sigma IR Antibody, clone ICR-SIG1R-A

    产品名称：Anti-Sigma IR Antibody, clone ICR-SIG1R-A
    产品型号：MABN390
    Detect the Sigma IR protein using this Anti-Sigma IR, clone ICR-SIG1R-A validated for use in wb, IP, ICC, Flow & IHC.

    merck millipore,默克密理博,MABN390,Anti-Sigma IR Antibody, clone ICR-SIG1R-A

  • 产品介绍
  • merck millipore,默克密理博,MABN390,Anti-Sigma IR Antibody, clone ICR-SIG1R-A

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    M, HIHC, WB, ICC, FCRPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABN390
    描述 Anti-Sigma IR Antibody, clone ICR-SIG1R-A
    Alternate Names
    • Sigma1R
    • Sigma non-opioid intracellular receptor 1
    • Sigma 1-type opioid receptor
    • Sigma1-receptor
    背景信息 Sigma1R, or Sigma non-opioid intracellular receptor 1, is part of the ERG2 family that forms a ternary complex with ANK2 and ITPR3. Sigma1R is involved in lipid transport from the endoplasmic reticulum, BDNF and EGF signaling, potassium ion channel regulation and other cell functions including apoptosis, survival and proliferation. It was initially discovered through its binding to various psychoactive drugs, and has been studied in memory, learning and mood alteration processes. Sigma1R is often found in the nuclear membrane, synapses and endoplasmic reticulum of cells within liver, brain, kidney and thymus tissues.
    产品信息
    格式 Purified
    控制
    • Colo-587 cell lysate
    演示 Purified rat monoclonal IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Detect the Sigma IR protein using this Anti-Sigma IR, clone ICR-SIG1R-A validated for use in wb, IP, ICC, Flow & IHC.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    • Immunocytochemistry
    • Flow Cytometry
    应用说明 Immunoprecipitation Analysis: A representative lot was used by an an independent laboratory to detect Sigma IR in certain cancer cell lysates.
    Immunocytochemistry Analysis: A representative lot was used by an independent laboratory to detect Sigma IR in human cancer cells including pancreatic carcinoma and sarcoma cell lines and xenografts.
    Flow Cytometry Analysis: A representative lot was used by an an independent laboratory to detect Sigma IR in tumor cells.
    Immunohistochemistry Analysis: A representative lot was used by an an independent laboratory to detect Sigma IR in human cancer cells including pancreatic carcinoma and sarcoma cell lines and xenografts.
    生物信息
    免疫原品种 Linear peptide corresponding to human Sigma IR.
    克隆 ICR-SIG1R-A
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rat
    同种型 IgG1
    品种反应性 MouseHuman
    Species Reactivity Note Demonstrated to react with Human. Predicted to react with Mouse based upon immunogen design.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_005857
    基因符号
    • SRBP
    • SIGMAR1
    • OPRS1
    纯化方法 Protein G purified
    UniProt编号
    • Q99720
    产品使用声明
    质量保证 Evaluated by Western Blotting in colo-587 cell lysate.

    Western Blotting Analysis: 1.0 µg/mL of this antibody detected Sigma IR in 10 µg of colo-587 cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MABN390,Anti-Sigma IR Antibody, clone ICR-SIG1R-A

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