merck millipore,默克密理博,MABN263,Anti-GABA(A) receptor subunit gamma-2 Antibody, clone 10F10-C1-B8

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
R	ICC, WB	M	Purified	Monoclonal Antibody

描述
产品目录编号	MABN263
描述	Anti-GABA(A) receptor subunit gamma-2 Antibody, clone 10F10-C1-B8
Alternate Names	GABA(A) receptor subunit gamma-2 Gamma-aminobutyric acid receptor subunit gamma-2
背景信息	GABA(A) receptor subunit gamma-2 is a protein belonging to a subclass of GABA receptors known as GABA (A). GABA (A) receptors are pentameric chloride channels composed of subunits belonging to different homology classes, i.e. α, β, γ, δ, θ, ε, π, and act as receptors for GABA, a crucial inhibitory neurotransmitter localized within the brain. GABA (A) gamma 2 subunit consists of 5 cysteine residues and carries the binding site for benzodiazepine. The subunit functions to promote receptor maintenance and clustering at the synapse, interacts with GABA receptor associated proteins such as GODZ and GABAWRAP, affects GABA (A) receptor conductance and kinetics, and is a contributing component to receptors participating in both phasic and tonic inhibition. Several mutations in the GABA(A) receptor subunit gamma-2 expression have been linked to epileptic syndromes that result in fibrile seizures.

产品信息
格式	Purified
控制	PC-12 cell lysate
演示	Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

应用
应用	Detect GABA(A) receptor subunit gamma-2 using this Anti-GABA(A) receptor subunit gamma-2 Antibody, clone 10F10-C1-B8 validated for use in Western Blotting, ICC.
主要应用	Immunocytochemistry Western Blotting
应用说明	Immunocytochemistry Analysis: A 1:250 dilution from a representative lot detected GABA(A) receptor subunit gamma-2 in rat hippocampal neurons. Image courtesy from the laboratory of Dr. Jaideep Kapur, University of Virginia.

生物信息
免疫原品种	Linear peptide corresponding to rat GABA(A) receptor subunit gamma-2.
克隆	10F10-C1-B8
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Mouse
同种型	IgG2bκ
品种反应性	Rat
Species Reactivity Note	Demonstrated to react with Rat.
抗体类型	Monoclonal Antibody
Entrez基因编号	NP_899156
基因符号	Gabrg2
纯化方法	Protein G purified
UniProt编号	P18508

产品使用声明
质量保证	Evaluated by Western Blot in PC-12 cell lysate. Western Blot Analysis: A 1:2,000 dilution of this antibody detected GABA(A) receptor subunit gamma-2 in 10 µg of PC-12 cell lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at 2-8°C from date of receipt.

包装信息
数量	100 µL

merck millipore,默克密理博,MABN263,Anti-GABA(A) receptor subunit gamma-2 Antibody, clone 10F10-C1-B8

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