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merck millipore,默克密理博,EZGRT-89K,Human Ghrelin (total) ELISA
产品名称：Human Ghrelin (total) ELISA
产品型号：EZGRT-89K
This Human Ghrelin (total) ELISA is used to measure & quantify Ghrelin (total) levels in Metabolism & Endocrine & Neuroscience research.
merck millipore,默克密理博,EZGRT-89K,Human Ghrelin (total) ELISA
- 产品介绍
重要规格表
可用的分析物 品种反应性 主要应用 检测方法 Ghrelin (Total) H ELISA Colorimetric, Fluorescent 描述 产品目录编号 EZGRT-89K 描述 Human Ghrelin (total) ELISA 背景信息 Circulating ghrelin is a multifunctional hormone secreted primarily by the stomach. 产品信息 检测方法 ColorimetricFluorescent 精度（%） - Intra-assay: Serum: 0.9–1.3% Plasma: 1.1–1.9%
- Inter-assay: Serum: 6.2–7.8% Plasma: 5.2–7.7%
应用 应用 This Human Ghrelin (total) ELISA is used to measure & quantify Ghrelin (total) levels in Metabolism & Endocrine & Neuroscience research. 主要应用 - ELISA
应用说明 Room temperature, 3 hour assay, 20 μL sample size (serum or plasma) 生物信息 特异性 Human Ghrelin (active) 80% Des-Octanoyl Human Ghrelin 100% Canine Ghrelin (active) 70% Porcine Ghrelin (active) not detectable Motilin Related Peptide (Human, Rat/Mouse) not detectable PYY 3-36 (Human, Mouse, Porcine) not detectable NPY (Human/Rat) 品种反应性 Human 可用的分析物 - Ghrelin (Total)
Entrez基因编号 - NM_016362.2
Entrez基因汇总 Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor (GHSR; MIM 601898) and is involved in regulating growth hormone (GH; MIM 139250) release. Ghrelin is derived from a preprohormone called preproghrelin, which also generates a second peptide called obestatin. Obestatin is an endogenous ligand for the orphan G protein-coupled receptor GPR39 (MIM 602886) and is involved in satiety and decreased food intake.[supplied by OMIM] 基因符号 - MTLRP
- GHRL
- ghrelin
- obestatin
UniProt编号 - Q9UBU3
UniProt汇总 FUNCTION: SwissProt: Q9UBU3 # Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility (By similarity).
SIZE: 117 amino acids; 12911 Da
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICITY: Highest level in stomach. All forms are found in serum as well. Other tissues compensate for the loss of ghrelin synthesis in the stomach following gastrectomy.
PTM: O-octanoylation or O-decanoylation is essential for ghrelin activity. The O-decanoylated forms Ghrelin-27-C10 and Ghrelin-28- C10 differ in the length of the carbon backbone of the carboxylic acid bound to Ser-26. A small fraction of ghrelin, ghrelin-28- C10:1, may be modified with a singly unsaturated carboxylic acid. & Amidation of Leu-98 is essential for obestatin activity (By similarity).
SIMILARITY: SwissProt: Q9UBU3 ## Belongs to the motilin family.准确度 - (Des-octanoyl Ghrelin) 112–119%
- Serum: (Active Ghrelin) 88–91%
- (Des-octanoyl Ghrelin) 101–107%
- Plasma: (Active Ghrelin) 84–87%
理化信息 灵敏度 - 30 pg/mL (20 µL sample size)
稀释的线性 Serum: 95.7–104.7% Plasma: 95–117% 产品使用声明 销售限制 This product is not available for sale in Japan. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
包装信息 数量 96-well strip plate
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