merck millipore,默克密理博,MABN1024,Anti-ARG1 Antibody, clone EPR6672(B), rabbit monoclonal

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merck millipore,默克密理博,MABN1024,Anti-ARG1 Antibody, clone EPR6672(B), rabbit monoclonal
产品名称：Anti-ARG1 Antibody, clone EPR6672(B), rabbit monoclonal
产品型号：MABN1024
Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target.

merck millipore,默克密理博,MABN1024,Anti-ARG1 Antibody, clone EPR6672(B), rabbit monoclonal

产品介绍

merck millipore,默克密理博,MABN1024,Anti-ARG1 Antibody, clone EPR6672(B), rabbit monoclonal

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
H	IHC, WB	Rb	Unpurified	Monoclonal Antibody

描述
产品目录编号	MABN1024
描述	Anti-ARG1 Antibody, clone EPR6672(B), rabbit monoclonal
Alternate Names	Type I arginase Arginase-1 Liver-type arginase
背景信息	Arginase-1, the protein encoded by the ARG1 gene, is the enzyme that catalyzes the breakdown of L-arginine into ornithine and urea and a key player in the Urea cycle. There are two distinct isoforms of Arginase, Arginase I and Arginase II. Arginase I (also called the liver type arginase or Type 1 arginase) is a highly expressed cytosolic enzyme in the liver and other tissues, including the brain. Arginase II or kidney-type arginase is also widely expressed at low levels in many tissues but localized to the mitochondria primarily. Interestingly Arginase 1 has neuroprotective properties. Arginase I is essential for protecting motor neurons from nitric oxide dependent apoptosis that can be induced upon cellular stress or trophic factor removal. By suppressing nitric oxide production, Arginase prevents the formation of peroxynitrite and its subsequent cellular toxicity. Furthermore, Arginase 1 appears to play critical roles throughout the CNS for survival and regeneration of neurons and axons. In cancer, Arginase 1, already a useful marker for hepatocytes is also an excellent marker for hepatocellular cancers. EMD-Millipore’s Anti-ARG1 rabbit monoclonal antibody has been tested in western blot on human fetal lung and liver extracts and in immunohistochemistry on paraffin embedded human hepatocellular carcinoma tissue.

产品信息
格式	Unpurified
控制	Human fetal liver and fetal lung tissue lysates
演示	Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.

应用
应用	Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target.
主要应用	Immunohistochemistry Western Blotting
应用说明	Immunohistochemistry Analysis: A 1:250-500 dilution from a representative lot detected ARG1 in human hepatocellular carcinoma tissue. Optimal working dilutions must be determined by end user.

生物信息
免疫原品种	Synthetic peptide corresponding to human ARG1.
克隆	EPR6672(B)
宿主	Rabbit
品种反应性	Human
抗体类型	Monoclonal Antibody
基因符号	ARG1
纯化方法	Unpurified
UniProt编号	P05089

产品使用声明
质量保证	Evaluated by Western Blotting in human fetal liver and fetal lung tissue lysates. Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected ARG1 in human fetal liver and fetal lung tissue lysates.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.