merck millipore,默克密理愽
  • merck millipore,默克密理博,MABF743,Anti-CD4 Antibody (mouse), PE-Cy5, clone GK1.5

  • merck millipore,默克密理博,MABF743,Anti-CD4 Antibody (mouse), PE-Cy5, clone GK1.5

    产品名称：Anti-CD4 Antibody (mouse), PE-Cy5, clone GK1.5
    产品型号：MABF743
    This Rat Monoclonal Antibody Anti-CD4 (mouse), PE-Cy5, clone GK1.5, Cat. No. MABF743 is validated for use in IP, IHC, FC for the detection of CD4.

    merck millipore,默克密理博,MABF743,Anti-CD4 Antibody (mouse), PE-Cy5, clone GK1.5

  • 产品介绍
  • merck millipore,默克密理博,MABF743,Anti-CD4 Antibody (mouse), PE-Cy5, clone GK1.5

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    MFC, IHCRPE-Cy5Monoclonal Antibody
    描述
    产品目录编号 MABF743
    描述 Anti-CD4 Antibody (mouse), PE-Cy5, clone GK1.5
    Alternate Names
    • CD44
    • CD44 antigen
    • Extracellular matrix receptor III
    • ECMR-III
    • GP90 lymphocyte homing/adhesion receptor
    • HUTCH-I
    • Hermes antigen
    • Hyaluronate receptor
    • Lymphocyte antigen 24
    • Ly-24
    • Phagocytic glycoprotein 1
    • PGP-1
    • Phagocytic glycoprotein I
    • PGP-I
    背景信息 The GK1.5 antibody reacts with mouse CD4, a 55 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4 is typically expressed on thymocytes, certain mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells.The GK1.5 antibody is widely used as a phenotypic marker for CD4 expression. If used together, the GK1.5 antibody and an alternative antibody, Anti-Mouse CD4 clone RM4-5, will “compete” for binding, i.e. RM4-5 is able to block GK1.5 binding to cells. In contrast, the Anti-Mouse CD4 clone RM4-4 does not block binding of the GK1.5 antibody to cells (Arora S et al. 2006. Infect. Immun. 74: 4339-4348). The GK1.5 antibody is also reported to be cross-reactive with Syrian hamster CD4.
    产品信息
    格式 PE-Cy5
    演示 Purified Rat Monoclonal Antibody in buffer containing 10 mM NaH2PO4, 150 mM NaCl, 0.1% gelatin, pH 7.2, and up to 0.1% sodium azide.
    应用
    应用 This Rat Monoclonal Antibody Anti-CD4 (mouse), PE-Cy5, clone GK1.5, Cat. No. MABF743 is validated for use in IP, IHC, FC for the detection of CD4.
    主要应用
    • Flow Cytometry
    • Immunohistochemistry
    生物信息
    免疫原品种 Immunogen information for this antibody is proprietary information.
    克隆 GK1.5
    浓缩 0.2 mg/mL
    宿主 Rat
    同种型 IgG2bκ
    品种反应性 Mouse
    抗体类型 Monoclonal Antibody
    基因符号
    • Ly-24
    • Cd44
    纯化方法 Size Exclusion Chromatography
    UniProt编号
    • P15379
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MABF743,Anti-CD4 Antibody (mouse), PE-Cy5, clone GK1.5

上一件merck millipore产品：merck millipore,默克密理博,GR11L,Anti-IGF-IR (Ab-1) Mouse mAb (αIR3)
下一件merck millipore产品：merck millipore,默克密理博,42600,Ultrafree-DA 离心超滤管


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