merck millipore,默克密理博,MABF723,Anti-CD86 (B7-2) Antibody (mouse), APC, clone GL-1

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
M	FC, IHC	R	APC	Monoclonal Antibody

描述
产品目录编号	MABF723
描述	Anti-CD86 (B7-2) Antibody (mouse), APC, clone GL-1
Alternate Names	CD86 T-lymphocyte activation antigen CD86 Activation B7-2 antigen Early T-cell costimulatory molecule 1 ETC-1
背景信息	The GL-1 antibody reacts with mouse CD86, also known as B7-2, an 80 kDa cell surface protein which is a ligand for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 can also bind a second B7 ligand known as CD80 (B7-1). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response. The GL-1 antibody may be used as a marker for CD86 expression on B cells, macrophages, and dendritic cells.

产品信息
格式	APC
演示	Purified Rat Monoclonal Antibody in buffer containing 10 mM NaH2PO4, 150 mM NaCl, 0.1% gelatin, pH 7.2, and up to 0.1% sodium azide.

应用
应用	This rat monoclonal antibody Anti-CD86 (B7-2) (mouse), APC, clone GL-1 validated for use in IHC, Immunofluorescence & Flow Cytometry for the detection of CD86 (B7-2).
主要应用	Flow Cytometry Immunohistochemistry

生物信息
免疫原品种	Immunogen information for this antibody is proprietary information.
克隆	GL-1 (GL1)
浓缩	0.2 mg/mL
宿主	Rat
同种型	IgG2aκ
品种反应性	Mouse
抗体类型	Monoclonal Antibody
基因符号	Cd86
纯化方法	Size Exclusion Chromatography
UniProt编号	P42082

产品使用声明
质量保证	The monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. Flow Cytometry Analysis: 0.06 μg of this antibody detected CD86 (B7-2) in one million C57Bl/6 splenocytes.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.

包装信息
数量	25 µg

merck millipore,默克密理博,MABF723,Anti-CD86 (B7-2) Antibody (mouse), APC, clone GL-1

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