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merck millipore,默克密理博,05-822,Anti-Rho (-A, -B, -C) Antibody, clone 3L74, rabbit monoclonal
产品名称：Anti-Rho (-A, -B, -C) Antibody, clone 3L74, rabbit monoclonal
产品型号：05-822
Anti-Rho (-A Antibody, -B, -C), clone 3L74 is an antibody against Rho (-A, -B, -C) for use in WB.
merck millipore,默克密理博,05-822,Anti-Rho (-A, -B, -C) Antibody, clone 3L74, rabbit monoclonal
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H WB Rb Purified Monoclonal Antibody 描述 产品目录编号 05-822 品牌系列 Upstate
商名 - Upstate
描述 Anti-Rho (-A, -B, -C) Antibody, clone 3L74, rabbit monoclonal 产品信息 格式 Purified 应用 应用 Anti-Rho (-A Antibody, -B, -C), clone 3L74 is an antibody against Rho (-A, -B, -C) for use in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 KLH-conjugated, synthetic peptide (SYPDTDVILMCFSIDSPDSLENKK) corresponding to amino acids 73-94 of human Rho (-A, -B, -C), with two terminal lysines added to increase peptide solubility 克隆 clone 3L74 宿主 Rabbit 特异性 Recognizes Rho (-A, -B, -C) 同种型 IgG 品种反应性 RatHuman Species Reactivity Note Broad species cross-reactivity expected based on sequence homology 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_001664
基因符号 - ARH12
- RHOA
- RHO12
- Rho12
- RhoA
- RHOH12
- H12
- ARHA
纯化方法 Protein A purfied UniProt编号 - P61586
UniProt汇总 FUNCTION: SwissProt: P61586 # Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders. May be an activator of PLCE1.
COFACTOR: Magnesium.
SIZE: 193 amino acids; 21768 Da
SUBUNIT: Binds PRKCL1, ROCK1 and ROCK2. Interacts with ARHGEF3, NET1 and RTKN. Interacts with PLCE1 and AKAP13.
SUBCELLULAR LOCATION: Membrane; Lipid-anchor.
DOMAIN: SwissProt: P61586 The basic-rich region is essential for yopT recognition and cleavage.
PTM: Substrate for botulinum ADP-ribosyltransferase. & Cleaved by yopT protease when the cell is infected by some Yersinia pathogens. This removes the lipid attachment, and leads to its displacement from plasma membrane and to subsequent cytoskeleton cleavage.
SIMILARITY: Belongs to the small GTPase superfamily. Rho family.产品使用声明 质量保证 routinely evaluated by immunoblot on modified RIPA lysates from HL-60 cells 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 2 years at -20°C from date of shipment 包装信息 数量 100 µL
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