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merck millipore,默克密理博,14-1057,Human native nucleosomes
产品名称：Human native nucleosomes
产品型号：14-1057
Human native nucleosomes purified from HeLa cell nuclei, digested with micrococcal nuclease & purified by glycerol gradient & ion exchange chromatography.
merck millipore,默克密理博,14-1057,Human native nucleosomes
- 产品介绍
重要规格表
主要应用 ACT 描述 产品目录编号 14-1057 品牌系列 Upstate
商名 - Upstate
描述 Human native nucleosomes 概述 Human native nucleosomes purified from HeLa cell nuclei, digested with micrococcal nuclease, and purified by glycerol gradient and ion exchange chromatography. 背景信息 Nucleosomes are the basic units of chromatin, and are comprised of approximately 147 bp of DNA spooled around a central octamer of core histones, H2A, H2B, H3, and H4. The arrangement of nucleosomes in chromatin can be altered by post-translational modifications (PTM) occurring on the C- and N-terminal tails of the core histones. Histone modifications can either provide or hinder access of key transcriptional complexes to DNA sequences and can regulate the expression of genes. These effects can be deciphered by applications such as chromatin immunoprecipiation (ChIP), which requires high quality chromatin, and essential tools such as histone proteins and appropriate enzymes, to assemble chromatin in vitro. 产品信息 演示 20 μg of mononucleosomes in buffer containing 20 mM Tris-Cl pH 7.9, 1 mM EDTA, 0.5 mM PMSF,1 mM DTT, and 50% glycerol. 应用 应用 Human native nucleosomes purified from HeLa cell nuclei, digested with micrococcal nuclease & purified by glycerol gradient & ion exchange chromatography. 主要应用 - Activity Assay
应用说明 Suitable for in vitro chromatin assembly and enzyme activity assays 生物信息 浓缩 0.2 µg/µL 纯度 >98% purity by SDS PAGE 来源 Human 产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable at -80ºC for 1 year from date of receipt. 包装信息 数量 20 µg
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