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merck millipore,默克密理博,MABF506,Anti-CD115 (c-fms) Antibody (mouse), APC, clone AFS98
产品名称:Anti-CD115 (c-fms) Antibody (mouse), APC, clone AFS98
产品型号:MABF506
This rat monoclonal antibody Anti-CD115 (c-fms) (mouse), APC, clone AFS98 validated for use in western blotting & Flow Cytometry for the detection of CD115 (c-fms).
merck millipore,默克密理博,MABF506,Anti-CD115 (c-fms) Antibody (mouse), APC, clone AFS98
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M FC R APC Monoclonal Antibody 描述 产品目录编号 MABF506 描述 Anti-CD115 (c-fms) Antibody (mouse), APC, clone AFS98 Alternate Names - CSF1-R
- Macrophage colony-stimulating factor 1 receptor
- CSF-1 receptor
- CSF-1-R
- CSF-1R
- M-CSF-R
- Proto-oncogene c-Fms
- CD115
背景信息 The AFS98 antibody is specific for mouse CD115, also known as Colony-Stimulating Factor-1 Receptor (CSF-1R), a 145 kDa receptor from the PDGF receptor family. Receptor activation by the ligands IL-34 or CSF-1 (M-CSF) occurs via homodimerization of CD115 and subsequent tyrosine phosphorylation and ubiquitination of intracellular domains. CD115 signaling promotes differentiation of myeloid precursors, as well as the continued regulation of proliferation, survival and function of mononuclear phagocytes, dendritic cells and osteoclasts. While IL-34 and CSF-1 may induce similar cellular responses, they are differentially expressed and as such exert complimentary actions via CD115.The AFS98 antibody may be used for identification of myeloid lineage cells by flow cytometry, and is commonly used for in vivo or in vitro neutralization of CSF-1 Receptor. 产品信息 格式 APC 演示 Purified Rat Monoclonal Antibody in buffer containing 10 mM NaH2PO4, 150 mM NaCl, 0.1% gelatin, pH 7.2, and up to 0.1% sodium azide. 应用 应用 This rat monoclonal antibody Anti-CD115 (c-fms) (mouse), APC, clone AFS98 validated for use in western blotting & Flow Cytometry for the detection of CD115 (c-fms). 主要应用 - Flow Cytometry
生物信息 免疫原品种 Immunogen information for this antibody is proprietary information. 克隆 AFS98 浓缩 0.2 mg/mL 宿主 Rat 同种型 IgG2aκ 品种反应性 Mouse 抗体类型 Monoclonal Antibody 基因符号 - Fms
- Csf1r
- Csfmr
纯化方法 Size Exclusion Chromatography UniProt编号 - P09581
产品使用声明 质量保证 The monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.
Flow Cytometry Analysis: 0.06 μg of this antibody detected CD115 (c-fms) in one million C57Bl/6 peripheral blood cells.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze. 包装信息 数量 25 µg
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