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品种反应性 主要应用 宿主 格式 抗体类型 M FC, WB R Purified Monoclonal Antibody 描述 产品目录编号 MABF37 描述 Anti-CD24 Antibody, clone M1/69 Alternate Names - CD24 antigen (small cell lung carcinoma cluster 4 antigen), CD24A
- Signal transducer CD24
- Small cell lung carcinoma cluster 4 antigen
- CD24 antigen
背景信息 The CD24 antigen (also known as Small cell lung carcinoma cluster 4 antigen), which has a molecular weight of 35-45 kDa, is a glycosyl phosphatidylinositol (GPI)-anchored surface molecule. It is a member of a family that also includes HSA and CD52. Cross-linking of CD24 can induce increased intracellular Ca++ in mature B lymphocytes (Turni, 2002).
CD24 is expressed at multiple stages of B cell development, beginning with the bone marrow CD34+ pro-B-cell compartment and continuing through mature surface IgM+/IgD+ B cells. Plasma cells express very low to negligible levels of CD24 (Le Bien, 1995). CD24 is not expressed on the cell surface of normal T cells or monocytes, but is expressed on mature granulocytes (Le Bien, 1995; Fukukawa, 1986). The antigen is also present on a variety of epithelial types (Turni, 2002).产品信息 格式 Purified 控制 - Mouse spleen tissue lysate
演示 Purified rat monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect CD24 using this Anti-CD24 Antibody, clone M1/69 validated for use in WB, FC. 主要应用 - Flow Cytometry
- Western Blotting
应用说明 Flow Cytometry Analysis: 2 µg from a previous lot detected CD24 in BALB/c splenocytes. 生物信息 免疫原品种 Whole B10 spleen cells 克隆 clone M1/69 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rat 同种型 IgG2bκ 品种反应性 Mouse Species Reactivity Note Demonstrated to react with mouse. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_033976
基因符号 - CD24A
- CD24
纯化方法 Protein G Purified UniProt编号 - P24807
UniProt汇总 FUNCTION: May have a specific role to play in early thymocyte development.
SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor › GPI-anchor.
TISSUE SPECIFICTY: In lymphoid, myeloid, and erythroid cells.
PTM: The identity of the N- and O-linked polysaccharides are not reported in Ref.6. The O-linked polysaccharides on Ser-30, Ser-41, Ser-43, and Thr-51 are probably the mucin type linked to GalNAc.
SEQUENCE SIMILARITIES: Belongs to the CD24 family.产品使用声明 质量保证 Evaluated by Western Blot in mouse spleen tissue lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected CD24 on 10 µg of mouse spleen tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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