merck millipore,默克密理愽
  • merck millipore,默克密理博,MABF355,Anti-CD45RO (human) Antibody, APC, clone UCHL1

  • merck millipore,默克密理博,MABF355,Anti-CD45RO (human) Antibody, APC, clone UCHL1

    产品名称：Anti-CD45RO (human) Antibody, APC, clone UCHL1
    产品型号：MABF355
    Detect CD45RO using this mouse monoclonal antibody, Anti-CD45RO (human) Antibody, APC, clone UCHL1 validated for use in Flow Cytometry, western blotting, IHC & IP.

    merck millipore,默克密理博,MABF355,Anti-CD45RO (human) Antibody, APC, clone UCHL1

  • 产品介绍
  • merck millipore,默克密理博,MABF355,Anti-CD45RO (human) Antibody, APC, clone UCHL1

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HIHC, FC, WBMAPCMonoclonal Antibody
    描述
    产品目录编号 MABF355
    描述 Anti-CD45RO (human) Antibody, APC, clone UCHL1
    Alternate Names
    • CD45RO
    • Receptor-type tyrosine-protein phosphatase C
    • Leukocyte common antigen
    • L-CA
    • T200
    • CD45
    背景信息 Receptor-type tyrosine-protein phosphatase C, also known as Leukocyte common antigen (L-CA) or CD45 and encoded by the human gene PTPRC or CD45 is a transmembrane glycoprotein that belongs to the PTP family. PTPs are signaling molecules that regulate cellular process like cell growth, differentiation and mitotic cycle. CD45 has many isoforms that are distributed throughout the immune system according to cell type. These arise because of alternative splicing of RA, RB, and RC exons. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45RO is one of the isoforms of CD45 that facilitates T cell activation. It is also the shortest isform which lack the RA, RB, and RC exons. Mutations in CD45 have been associated with mulitple sclerosis and severe combined immunodeficiency.
    产品信息
    格式 APC
    演示 Purified mouse conjugate antibody in buffer containing PBS (pH 7.2) with up to 0.1% sodium azide and 0.2% (w/v) BSA.
    应用
    应用 Detect CD45RO using this mouse monoclonal antibody, Anti-CD45RO (human) Antibody, APC, clone UCHL1 validated for use in Flow Cytometry, western blotting, IHC & IP.
    主要应用
    • Immunohistochemistry
    • Flow Cytometry
    • Western Blotting
    应用说明 Western Blotting Analysis: A representative lot detected human CD45RO in Western Blotting. (Ishii T, et al. 2001.)

    Immunohistochemistry Analysis: A representative lot detected human CD45RO in Immunohistochemistry. (Yamada M, et al.1996.;Sakkas LI, et al. 1998.)

    Immunoprecipitation Analysis: A representative lot detected human CD45RO in Immunoprecipitation. (Ponsford M, et al. 2001.)
    生物信息
    免疫原品种 Cultured T cells from an IL-2 dependent T-cell line (CA1) prepared from human peripheral blood.
    克隆 UCHL1
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 This antibody is commonly used in combination with antibodies against CD45RA to discern memory and naïve T cells.
    同种型 IgG2aκ
    品种反应性 Human
    Species Reactivity Note Human
    抗体类型 Monoclonal Antibody
    基因符号
    • PTPRC
    • CD45
    纯化方法 Affinity
    UniProt编号
    • P08575
    产品使用声明
    质量保证 The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

    Flow Cytometry Analysis: 5 μL of this antibody detected CD45RO in one million human peripheral blood lymphocytes.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 The antibody solution should be stored undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
    包装信息
    数量 100 tests

    merck millipore,默克密理博,MABF355,Anti-CD45RO (human) Antibody, APC, clone UCHL1

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