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merck millipore,默克密理博,MABC522,Anti-MAP17 Antibody, clone 165C
产品名称：Anti-MAP17 Antibody, clone 165C
产品型号：MABC522
Anti-MAP17 Antibody, clone 165C is a highly specific mouse monoclonal antibody, that targets MAP17 & has been tested in western blotting & IHC.
merck millipore,默克密理博,MABC522,Anti-MAP17 Antibody, clone 165C
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H IHC, WB M Purified Monoclonal Antibody 描述 产品目录编号 MABC522 描述 Anti-MAP17 Antibody, clone 165C Alternate Names - Protein DD96
- PDZK1-interacting protein 1
- 17 kDa membrane-associated protein
背景信息 The protein named PDZK1-interacting protein 1 or alternatively 17kDa membrane-associated protein DD96 or MAP17 and encoded by the human gene named PDZK1IP1 or MAP17 is a highly unusual protein being naturally expressed only in a single epithelial cell population found in the proximal tubular epithelial cells. However, MAP17 is expressed in cancerous tissue of the kidney, colon, lung and breast. MAP17 expression in cancers causes an increase in reactive oxygen species production and tumorigenesis in cancerous tissues. These factors are mediated though MAP17’s PDZ-binding domain because disruption of this sequence by point mutations abolishes the ability of MAP17 to enhance ROS production and tumorigenesis. MAP17 also often serves as a cancer cell marker to distinguish tumor margins and tumorigenesis potential. MAP17 is a membrane bound protein and is thought to be a putative oncogene but its exact function in normal cells is still being researched. 产品信息 格式 Purified 演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-MAP17 Antibody, clone 165C is a highly specific mouse monoclonal antibody, that targets MAP17 & has been tested in western blotting & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Western Blotting Analysis: 1.0 µg/mL from a representative lot detected MAP17 in 10 µg of human salivary gland tissue lysate.
Immunohistochemistry Analysis: A 1:500-2,000 dilution from a representative lot detected MAP17 in human prostate cancer and human kidney tissue.生物信息 免疫原品种 GST-tagged recombinant protein corresponding to human MAP17. 克隆 165C 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG1κ 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_005755
基因符号 - MAP17
- PDZK1IP1
纯化方法 Protein G purified UniProt编号 - Q13113
产品使用声明 质量保证 Evaluated by Western Blotting in human kidney tissue lysate.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected MAP17 in 10 µg of human kidney tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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