merck millipore,默克密理博,MABE565,Anti-HIRA Antibody, clone EPR7416, rabbit monoclonal

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merck millipore,默克密理博,MABE565,Anti-HIRA Antibody, clone EPR7416, rabbit monoclonal
产品名称：Anti-HIRA Antibody, clone EPR7416, rabbit monoclonal
产品型号：MABE565
Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target.

merck millipore,默克密理博,MABE565,Anti-HIRA Antibody, clone EPR7416, rabbit monoclonal

产品介绍

merck millipore,默克密理博,MABE565,Anti-HIRA Antibody, clone EPR7416, rabbit monoclonal

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
H	WB	Rb	Unpurified	Monoclonal Antibody

描述
产品目录编号	MABE565
描述	Anti-HIRA Antibody, clone EPR7416, rabbit monoclonal
Alternate Names	TUP1-like enhancer of split protein 1 Protein HIRA
背景信息	HIRA protein, also known as TUP1-like enhancer of split protein 1, encoded by the HIRA gene (also named DGCR1, HIR, and TUPLE1) is required for the repression of histone gene transcription and for the formation of senescence associated heterochromatin foci (SAHF) and for the efficient exit from senescence associated cell cycle rest. HIRA also cooperates with another chromatin protein, ASF1A to promote replication-independent chromatin assembly. HIRA seems to be a sort of histone chaperone, particularly with histone H3 and its variants and acts to deposit the histone into chromatin which is then linked to gene activation, repression, and chromatin assembly in diverse cell contexts. EMD-Millipore’s Anti-HIRA rabbit monoclonal antibody has been tested in western blot on 293T, HeLa, and K562 cell lysates and in fluorescent immunocytochemistry on HeLa cells in culture.

产品信息
格式	Unpurified
控制	293T, HeLa, and K562 cell lysates
演示	Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.

应用
应用	Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target.
主要应用	Western Blotting
应用说明	Immunofluorescence Analysis: A 1:50-100 dilution from a representative lot detected HIRA in HeLa cells. Optimal working dilutions must be determined by end user.

生物信息
免疫原品种	Synthetic peptide corresponding to human HIRA.
克隆	EPR7416
宿主	Rabbit
品种反应性	Human
抗体类型	Monoclonal Antibody
基因符号	TUPLE1 HIRA DGCR1 HIR
纯化方法	Unpurified
UniProt编号	P54198

产品使用声明
质量保证	Evaluated by Western Blotting in 293T, HeLa, and K562 cell lysates. Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected HIRA in 293T, HeLa, and K562 cell lysates.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.