- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H, M WB R Purified Monoclonal Antibody 描述 产品目录编号 MABE431 描述 Anti-PRMT1 Antibody, clone 7D2 Alternate Names - Interferon receptor 1-bound protein 4
- Protein arginine N-methyltransferase 1
- Histone-arginine N-methyltransferase PRMT1
背景信息 The methylation of arginine is mediated by the Protein Arginine Methyl Transferase (PRMT) family of enzymes. These enzymes transfer the methyl group from S-adenosyl-Lmethionine to the guanidino nitrogen atoms of an arginine residue. Arginine methylation was found to be an important modification in signal transduction, transcription, RNA transport, and splicing. PRMT1, also known as HRMT1L2 and IR1B4, was isolated through its interaction with BTG1 and TIS21, proteins that are important in cell quiescence. PRMT1 is a 361 amino acid protein; its splicing variants differ at the N-terminus, giving rise to three isoforms of 343, 361, and 347 amino acids (variants 1, 2, and 3 respectively). Proteins involved in the metabolism of RNA are substrates for PRMT1, among them Sam68. 产品信息 格式 Purified 控制 - HEK293 cell lysate.
演示 Purified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect PRMT1 using this rat monoclonal antibody, Anti-PRMT1 Antibody & clone 7D2 validated for use in western blotting. 主要应用 - Western Blotting
应用说明 Western Blotting Analysis: A representative lot from an independent laboratory detected PRMT1 in E. Coli containing untagged PRMT1, E.Coli extract containing His-tagged PRMT1, E.Coli extract containing GST- tagged PRMT1, and in DG75 whole cell extract (Gross, H., et al. (2012). PLoS ONE. 7(8):e42106.). 生物信息 免疫原品种 BSA-conjugated linear peptide corresponding to human PRMT1. 克隆 7D2 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rat 同种型 IgG2aκ 品种反应性 RatHumanMouse 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_001527
基因符号 - IR1B4
- PRMT1
- HMT2
- HRMT1L2
纯化方法 Protein G purified UniProt编号 - Q99873
产品使用声明 质量保证 Evaluated by Western Blotting in HEK293 cell lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected PRMT1 in 10 µg of HEK293 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,SF-1279,PICALM; Human, Cyanine 3 RNA Detection Probe,SmartFlare
下一件merck millipore产品：merck millipore,默克密理博,AB1529,Anti-Nitric Oxide Synthase I Antibody
相关产品
merck millipore,默克密理博,MABN371,Anti-KChIP2 potassium channel subunit Antibody, clone 60/73
merck millipore,默克密理博,ABE343,Anti-phospho-Chk2 (Thr68) Antibody
merck millipore,默克密理博,AP147B,Rabbit Anti-Sheep IgG Antibody, biotin-SP conjugate
merck millipore,默克密理博,SF-1279,PICALM; Human, Cyanine 3 RNA Detection Probe,SmartFlare
merck millipore,默克密理博,AB1529,Anti-Nitric Oxide Synthase I Antibody
merck millipore,默克密理博,05-680,Anti-C-TAK1 (cdc25C associated protein kinase) Antibody
merck millipore,默克密理博,CP26,Anti-Integrin β₁ Mouse mAb (4B7)
merck millipore,默克密理博,05-321MG,Anti-Phosphotyrosine Antibody, clone 4G10
