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merck millipore,默克密理博,MABE347,Anti-H2A.Z.2.2 Antibody, clone 1H11-11
产品名称：Anti-H2A.Z.2.2 Antibody, clone 1H11-11
产品型号：MABE347
Anti-H2A.Z.2.2 Antibody, clone 1H11-11 is a highly specific rat monoclonal antibody & that targets Histone H2A.Z & has been tested in western blotting.
merck millipore,默克密理博,MABE347,Anti-H2A.Z.2.2 Antibody, clone 1H11-11
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB R Purified Monoclonal Antibody 描述 产品目录编号 MABE347 描述 Anti-H2A.Z.2.2 Antibody, clone 1H11-11 Alternate Names - H2A/z
- Histone H2A.Z
背景信息 H2A.Z.2.2 is an alternatively spliced histone H2A.Z variant. H2A.Z, also known as H2AFZ, is a variant of histone H2A variant that is highly conserved from yeast to humans. H2A.Z is involved in chromatin compaction by stabilizing the histone octamer within the nucleosome. It promotes gene expression through the creation of an open domain of chromatin that is more easily transcribed. H2A.Z is associated with both euchromatin and facultative heterochromatin. DNA methylation can influence chromatin structure and effect gene silencing by excluding H2A.Z, and likewise, H2A.Z protects genes from DNA methylation. Thus, H2A.Z plays a role in regulating heterochromatin silencing and is involved in transcriptional control. H2A.Z.2.2 has been demonstrated to cause nucleosome destabilization. 产品信息 格式 Purified 控制 - HeLa cell lysate
演示 Purified rat monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-H2A.Z.2.2 Antibody, clone 1H11-11 is a highly specific rat monoclonal antibody & that targets Histone H2A.Z & has been tested in western blotting. 主要应用 - Western Blotting
应用说明 Western Blot Analysis: A representative lot was used by an an independent laboratory to detect H2A.Z.2.2 in western blot. (Bonisch, C., et al. (2012). Nucleic Acids Research. 1-14). 生物信息 免疫原品种 BSA-conjugated linear peptide corresponding to the C-terminus of human H2A.Z.2.2. 表位 C-terminus 克隆 1H11-11 宿主 Rat 特异性 This antibody recognizes the C-terminus of H2A.Z.2.2, but does not demonstrate cross reactivity with H2A.Z.2.1 (Bonisch, C., et al. (2012). Nucleic Acids Research. 1-14). 同种型 IgG1κ 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_002097
基因符号 - H2AZ
- H2AFZ
纯化方法 Protein G purified UniProt编号 - P0C0S5
产品使用声明 质量保证 Evaluated by Western Blot in HeLa cell lysate.
Western Blot Analysis: A 1:2,000 dilution of this antibody detected H2A.Z.2.2 in 10 µg of HeLa cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µL
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