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品种反应性 主要应用 宿主 格式 抗体类型 H IHC, WB M Purified Monoclonal Antibody 描述 产品目录编号 MABE142 描述 Anti-Sirt6 Antibody, clone 6G2.2 Alternate Names - Oligodendrocyte-specific protein
- Claudin-11
背景信息 SIRT6 is one of seven mammalian homologs of the yeast Sir2 histone deacetylase. SIRT6 is a nuclear, chromatin-associated protein that is very important in normal DNA repair and resistance to DNA damage. SIRT6-deficient mice develop severe abnormalities that seem to be closely related to models of normal aging-associated degeneration and die at 4 weeks. SIRT6 has also been associated with other aging-related pathways and may be responsible for normal longevity and homeostasis. Recently, SIRT6 has also been shown to play an important role in glucose metabolism. 产品信息 格式 Purified 控制 - HeLa cell lysate
演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 This Anti-Sirt6 Antibody, clone 6G2.2 is validated for use in Western Blotting, IHC for the detection of Sirt6. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:25 dilution from a representative lot detected Sirt6 in human ovarian cancer tissues. 生物信息 免疫原品种 GST-tagged recombinant protein corresponding to human Sirt6. 克隆 6G2.2 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 同种型 IgG1κ 品种反应性 Human Species Reactivity Note Demonstrated to react with Human. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_057623
基因符号 - OTM
- CLDN11
- OSP
纯化方法 Protein G purified UniProt编号 - Q8N6T7
产品使用声明 质量保证 Evaluated by Western Blot in HeLa cell lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected Sirt6 in 10 µg of HeLa cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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下一件merck millipore产品：merck millipore,默克密理博,AB5574-200UL,Anti-TrpC6 Antibody
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