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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABC429 描述 Anti-VEGF-B Antibody Alternate Names - VRF
- Vascular endothelial growth factor B
- VEGF-B
- VEGF-related factor
背景信息 VEGF-B, also known as Vascular endothelial growth factor B, VEGF-related factor, VRF, and encoded by the gene VEGFB/VRF, is an endothelial cell growth factor that has multiple splice variants and plays roles in angiogenesis but also in cardiac muscle function, coronary vascular development, chemotaxis of endothelial cells and mast cells, apoptosis regulation, platelet activation, cell division, wound healing and the activation of various signaling pathways. VEGFB is a secreted protein that stays associated with cells because of its ability to bind to heparin. VEGFB is expressed in all cells except for liver cells with the highest levels found in muscle and pancreatic cells. VEGFB levels in plasma are also being studied as a potential biomarker for ventricle damage after heart attacks. High levels of plasma VEGFB show little remodeling whereas patients with lower levels had significant ventricle remodeling, thus VEGFB may have clinical utility in the identification of patients at high risk of remodeling and therefore ventricle damage. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect VEGF-B using this Anti-VEGF-B Antibody validated for use in western blotting & IHC (Paraffin). 主要应用 - Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected VEGF-B in human skeletal muscle myocytes and vascular tissue and cardiac myocytes in human heart. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human VEGF-B. 表位 Unknown 浓缩 1 mg/mL 宿主 Rabbit 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_003368
基因符号 - VRF
- VEGFB
纯化方法 Affinity purified UniProt编号 - P49765
产品使用声明 质量保证 Evaluated by Western Blotting in human skeletal muscle tissue lysate.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected VEGF-B in 10 µg of human skeletal muscle tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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