merck millipore,默克密理博,MABD70,Anti-Novel hES cell marker CC9 Antibody, clone CC9-D6-D5

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
H	WB, ICC, FC, IHC	M	Purified	Monoclonal Antibody

描述
产品目录编号	MABD70
描述	Anti-Novel hES cell marker CC9 Antibody, clone CC9-D6-D5
背景信息	Stem cells are unspecialized cells capable of renewing themselves through cell division and can differentiate into diverse specialized cell types. Embryonic stem cells, as the name suggests, are derived from embryos. Stem cell markers refer to the cell surface receptors that selectively bind signaling molecules. Each cell type has a unique combination of receptors on their surface that makes each cell type distinguishable from other kinds of cells. Novel hES cell marker CC9 binds a panel of ES and EC cells with a marked reduction in binding to NTERA-2 cells upon retinoic acid-induced differentiation. The epitope bound by this MAb is likely to be a cell surface carbohydrate residue, as treatment of 2102Ep with neuraminidase markedly reduces antibody binding. In cell staining this MAb shows differential staining between undifferentiated and differentiated regions of cells within the hESC culture, although at high concentrations some background staining on matrigel and fibroblast feeders is observed.

产品信息
格式	Purified
控制	H9 Human embryonic stem cells
演示	Purified mouse monoclonal IgMκ in PBS with 0.05% sodium azide.

应用
应用	Anti-Novel hES cell marker CC9 Antibody, clone CC9-D6-D5 is an antibody against Novel hES cell marker CC9 for use in IC, FC, IH & WB.
主要应用	Western Blotting Immunocytochemistry Flow Cytometry Immunohistochemistry
应用说明	Flow Cytometry Analysis: A representative lot was used by an independent laboratory to analyze human embryonic stem cells and embryonic carcinoma cells (Wright, A., et al. (2011). Int J Androl. 34(4 Pt 2):e175-e187). Immunohistochemistry Analysis: A representative lot was used by an independent laboratory in human testicular germ cell tumors (Wright, A., et al. (2011). Int J Androl. 34(4 Pt 2):e175-e187). Western Blot Analysis: A representative lot was used by an independent laboratory in n2102Ep cell lysate (Wright, A., et al. (2011). Int J Androl. 34(4 Pt 2):e175-e187).

生物信息
免疫原品种	Shef-1 human embryonic stem cells
克隆	CC9-D6-D5
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Mouse
特异性	This antibody exhibits high reactivity to both human embryonic stem (ES) cells and embryonal carcinoma (EC) cells similar to SSEA3 and TRA-1-60 (Wright, A., et al. (2011). Int J Androl. 34(4 Pt 2):e175-e187).
同种型	IgMκ
品种反应性	Human
Species Reactivity Note	Demonstrated to react with Human.
抗体类型	Monoclonal Antibody
纯化方法	Purified by ion exchange chromatography

产品使用声明
质量保证	Evaluated by Immunocytochemistry in H9 human embryonic stem cells. Immunocytochemistry Analysis: A 1:500 dilution of this antibody stained the cytosol of H9 human embryonic stem cells.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at 2-8°C from date of receipt.

包装信息
数量	100 µg

merck millipore,默克密理博,MABD70,Anti-Novel hES cell marker CC9 Antibody, clone CC9-D6-D5

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