merck millipore,默克密理博,MABD184,Anti-Noggin Antibody, clone EPR1561, rabbit monoclonal

搜索"Merck Millipore 密理愽"产品

Merck Millipore 默克密理愽

当前位置：首页 > >Merck Millipore > 生命科学研究
生命科学研究

merck millipore,默克密理博,MABD184,Anti-Noggin Antibody, clone EPR1561, rabbit monoclonal
产品名称：Anti-Noggin Antibody, clone EPR1561, rabbit monoclonal
产品型号：MABD184
Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target. Detect Noggin using this rabbit monoclonal antibody, More>>

merck millipore,默克密理博,MABD184,Anti-Noggin Antibody, clone EPR1561, rabbit monoclonal

产品介绍

merck millipore,默克密理博,MABD184,Anti-Noggin Antibody, clone EPR1561, rabbit monoclonal

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
H	WB	Rb	Unpurified	Monoclonal Antibody

描述
产品目录编号	MABD184
描述	Anti-Noggin Antibody, clone EPR1561, rabbit monoclonal
Alternate Names	Noggin
背景信息	Noggin protein, encoded by the gene named NOG, is an essential secreted polypeptide important for proper development and morphogenesis of many systems including, nervous, cartilage, and bone. Noggin appears to act by inhibiting the action of TGF-beta signaling proteins such as BMP4, BMP2 and BMP7 on their receptors as they diffuse through the extracellular matrix during growth and development. In doing so then, Noggin acts as an extracellular conveyor and regulator of morphogenic growth. In disease, Noggin defects in humans are associated with multiple synostosis syndrome (SYNS1) which appears to be a hypomorphic situation where not enough effective Noggin is produced. Interestingly recent research demonstrates that Noggin overexpression may help to protect adult brain against hypoxia and ischemic injury by selectively inhibiting the actions of BMP proteins known to be induced during injury, however over expression of Noggin is also associated with many aggressive and invasive bone cancers as well. EMD-Millipore’s Anti-Noggin rabbit monoclonal antibody has been tested in western blot on recombinant human Noggin protein.

产品信息
格式	Unpurified
控制	Human recombinant Noggin protein
演示	Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.

应用
应用	Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target. Detect Noggin using this rabbit monoclonal antibody, Anti-Noggin Antibody & clone EPR1561 validated for use in western blotting.
主要应用	Western Blotting

生物信息
免疫原品种	Synthetic peptide corresponding to human Noggin.
克隆	EPR1561
宿主	Rabbit
品种反应性	Human
抗体类型	Monoclonal Antibody
基因符号	NOG
纯化方法	Unpurified
UniProt编号	Q13253

产品使用声明
质量保证	Evaluated by Western Blotting in human recombinant Noggin protein. Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected human recombinant Noggin protein. Optimal working dilutions must be determined by end user.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.